Results 31 to 40 of about 4,231,166 (281)

Betriebliches Gesundheitsmanagement bei der CALIDA AG [PDF]

open access: yes, 2022
Das betriebliche Gesundheitsmanagement als Fachstelle soll die Gesundheit, das Wohlbefinden und die Motivation von Mitarbeitenden erhalten, fördern und verbessern.
Erni, Eliane
core   +1 more source

Effect of minor Ag on microstructure and mechanical properties of ZL114A aluminum alloy

open access: yesCailiao gongcheng, 2021
The effects of trace element Ag on the mechanical properties and microstructure of ZL114A aluminum alloy were investigated by the universal electron tensile testing machine, optical microscopy, scanning electron microscopy and spherical aberration ...
WU Zhen   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Formation of Cu, Ag and Au nanofiims under the influence of hydrogen atoms

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2015
Due to their electrical properties, thin metallic films are widely used in modern micro- and nanoelectronics. These properties allow solving fundamental problems of surface and solid state physics.
E. L. Zhavzharov, V. M. Matyushin
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Simultaneous Determination of Ag, W and Mo in Geochemical Exploration Samples by ICP-MS Using P507 Loaded Foam for Separation

open access: yesYankuang ceshi, 2014
When determining Ag in geochemical exploration samples by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS), the molecular ions 91Zr16O and 93Nb16O can seriously interfere with the isotopes 107Ag and 109Ag and need to be separated out to obtain ...
XING Zhi, QI Liang
doaj   +2 more sources

Room Temperature Coated Silver Thin Films using a Modified Chemical Bath Deposition Method for Surface-Enhanced Raman Scattering

open access: yesES General
The development of straightforward methods for fabricating thin-film substrates with adjustable surface-enhanced Raman scattering (SERS) efficiency and determining the best conditions to maximise the enhancement factor (EF) is essential.
Prathamesh Kadam   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Doping the thin films by using the original Close Space Sublimation method

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2020
The review is devoted to the results of studies on the structure, morphology, optical and luminescent properties of thin films doped with the modified Close Space Sublimation method.
V.S. Khomchenko   +3 more
doaj   +1 more source

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