Results 41 to 50 of about 2,564,040 (287)

Development of MEMS-in-TEM Setup to Observe Shear Deformation for the Study of Nano-Scale Friction

Tribology Online, 2011
Observing the atomic-level deformation of a frictional interface in real-time is important step to elucidate the mechanism of lubrication. We have combined the nano-scale handling capabilities of MEMS technology with the unsurpassed observation ability ...
Takaaki Sato, Tadashi Ishida, Laurent Jalabert, Hiroyuki Fujita   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Synergistic Effects of Cellulose Nanofibers and Coinage Metal Nanoparticles (Ag, CuO, and ZnO) in Active Packaging Biocomposites

Journal of Applied Science and Engineering
This study delves into the synthesis and characterization of cellulose nanofibers (NFCs) and their nanobiocomposites incorporating coinage nanoparticles ( Ag,ZnO, and CuO ).
I Putu Mahendra, Laurenz Yulindry Sihombing, Sahri Tarigan, Renaldi Malay, Khatarina Meldawati Pasaribu   +4 more
doaj   +1 more source

The Photocatalytic Activity of SiO2-TiO2/Graphite and Its Composite with Silver and Silver oxide

Bulletin of Chemical Reaction Engineering & Catalysis, 2014
This research study the mixed semiconductor of SiO2-TiO2 which was immobilized on graphite substrate and also studies the effect of surface modification on its mixed semiconductor. The surface modification was carried out by electrode position of Ag from
Fitria Rahmawati, Sayekti Wahyuningsih, Dian Irianti   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Functionalized SWCNTs@Ag–TiO2 nanocomposites induce ROS-mediated apoptosis and autophagy in liver cancer cells

Nanotechnology Reviews, 2023
Hybrid nanomaterials with unique physiochemical properties have received a lot of attention, making them attractive for application in different fields like cancer treatment.
Jabir Majid S., Mohammed Mustafa K. A., Albukhaty Salim, Ahmed Duha S., Syed Asad, Elgorban Abdallah M., Eswaramoorthy Rajalakshmanan, Al-kuraishy Hayder M., Al-Gareeb Ali I., Ghotekar Suresh, Jawad Sabrean F., Najm Mazin A. A.   +11 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Determination of Trace Amounts of Pb, Cd, Cu and Ag in High Salinity Water by ICP-AES with Sulfhydryl Cotton Separation and Preconcentration

Yankuang ceshi, 2014
Wastewater from mining enterprises contains a variety of heavy metals, and therefore requires treatment before discharge to render it non-toxic. After treatment by chemical precipitation, the content of metal is extremely low but has a large amount of ...
ZHANG Ning, GUO Xiu-ping, LI Xing, SHEN Yu-min, JIANG Yun-jun, AN Cai-xiu, XUE Zhi-kun   +6 more
doaj   +2 more sources