Results 61 to 70 of about 4,231,166 (281)

Molecular identification of a Bacillus cereus strain from Murrah buffalo milk showed in vitro bioremediation properties on selective heavy metals

open access: yesJournal of Advanced Veterinary and Animal Research, 2020
Objective: This study aims for molecular identification of naturally growing Bacillus cereus strain from a unique source, able to survive, and alleviate heavy metals from the nature.
Salauddin Al Azad   +4 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Immobilization of Antimicrobial Silver and Antioxidant Flavonoid as a Coating for Wound Dressing Materials

open access: yesInternational Journal of Nanomedicine, 2019
Hien A Tran,1–4 Khanh L Ly,4 Kate E Fox,5 Phong A Tran,1–3 Thi-Hiep Nguyen4 1Queensland University of Technology (QUT), Brisbane, Queensland 4001, Australia; 2Interface Science and Materials Engineering Group, School of Chemistry, Physics and
Tran HA   +4 more
doaj  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Synergistic Effects of Cellulose Nanofibers and Coinage Metal Nanoparticles (Ag, CuO, and ZnO) in Active Packaging Biocomposites

open access: yesJournal of Applied Science and Engineering
This study delves into the synthesis and characterization of cellulose nanofibers (NFCs) and their nanobiocomposites incorporating coinage nanoparticles ( Ag,ZnO, and CuO ).
I Putu Mahendra   +4 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Krisenkommunikationskonzept der Sihlsana AG

open access: yes, 2020
Die Sihlsana AG hat kein Krisenkommunikationskonzept mit definierten Prozessen,  Zuständigkeiten und und Hilfsmaterialien, welche für die Kommunikation in einer Krise  verwendet werden können.
Cuskic, Neven, Emini, Argtim
core  

Brasagem sem fluxo entre aço carbono e cobre com metais de adição convencionais à base de Ag e com revestimento metálico de Sn / [PDF]

open access: yes, 1999
Tese (Doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Estudou-se a brasagem sem fluxo entre aço carbono e cobre buscando avaliar a influência dos materiais base, dos metais de adição, das atmosferas de brasagem e do ciclo térmico ...
Okimoto, Paulo Cesar
core  

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