Results 81 to 90 of about 3,933,827 (279)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Ctla-4, una molécula que inhibe la activación de los linfocitos T

Salud Uninorte, 2006
CTLA-4 (Antígeno-4 asociado al Linfocito T Citotóxico) es una molécula expresada en la superficie de la mayoría de los linfocitos T activados. Su función es regular la homeostasis y la tolerancia periférica inmunológica inhibiendo la activación de los ...
Cecilia Fernández-Ponce, Juan David Hernández-Martínez, Carlos Silvera-Redondo   +2 more
doaj  

Stärkung der Positionierung und Kommunikation des Architekturbereichs der Quadrat AG

, 2023
Aus Überzeugung agiert das Quadrat konsequent verantwortungsvoll für Natur, Mensch und Mitwelt. Das Konzept der Kreislaufwirtschaft treibt das Unternehmen an.
Moret, Dominic, Lesaj, Sabine
core  

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Risk Management Sports and Leisure Center Tägi AG

, 2023
Today risk management is a critical topic for a company’s competitive advantage and value-generation process. While Tägi AG is on the right track and has risk management measures in place, those have not been structured or documented systemically ...
Zeder, Fabienne, Küffer, Jessica
core  

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Pulsed laser synthesis of highly active Ag–Rh and Ag–Pt antenna–reactor-type plasmonic catalysts

Beilstein Journal of Nanotechnology, 2019
Ag, Pt, and Rh monometallic colloids were produced via laser ablation. Separate Ag–Rh and Ag–Pt heterostructures were formed by mixing and resulted in groupings of Rh/Pt nanoparticles adsorbing to the concavities of the larger Ag nanostructures.
Kenneth A. Kane, Massimo F. Bertino
doaj   +1 more source

AG Digitale GW

, 2013
Die AG Digitale Geschichtswissenschaft im Verband der Historiker und Historikerinnen Deutschlands e.V. wurde auf dem Mainzer Historikertag im September 2012 gegründet. Sie wirkt darauf hin, die Potenziale der Digital Humanities bzw.
AG Digitale GW
core  

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source