Results 31 to 40 of about 18,379 (288)
COVID-19 and X-linked agammaglobulinemia (XLA) – insights from a monogenic antibody deficiency
Current Opinion in Allergy and Clinical Immunology, 2021 Purpose of review The clinical outcomes from COVID-19 in monogenic causes of predominant antibody deficiency have pivotal implications for our understanding of the antiviral contribution of humoral immunity.
Mark J. Ponsford +4 more
semanticscholar +1 more source
Journal of Clinical Immunology, 2021 To the Editor: Over the past year, the coronavirus disease 2019 (COVID19) has resulted in a worldwide pandemic. The disease results in a wide range of clinical presentations that range from asymptomatic to respiratory failure and death. To date, only two
Aled Iaboni, N. Wong, S. Betschel
semanticscholar +1 more source
The CRISPR Journal, 2021 X-linked agammaglobulinemia (XLA) is a monogenic primary immune deficiency characterized by very low levels of immunoglobulins and greatly increased risks for recurrent and severe infections.
David Gray +7 more
semanticscholar +1 more source
Tubulointerstitial nephritis complicating IVIG therapy for X-linked agammaglobulinemia [PDF]
, 2014 BACKGROUND: Patients with X-linked agammaglobulinemia (XLA) develop immune-complex induced diseases such as nephropathy only rarely, presumably because their immunoglobulin (Ig) G concentration is low.
Akane Izu +7 more
core +5 more sources
Revista Peruana de Medicina Experimental y Salud Pública, 2019 Primary agammaglobulinemia result from specific alterations in B cells, which lead to low antibody production. Diagnostic suspicion is established with a history of repeated infections, low immunoglobulins, and absence of CD19+ B lymphocytes.
Edgar Matos-Benavides +4 more
doaj +1 more source
Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA). [PDF]
, 1994 The gene responsible for X-linked agammaglobulinemia (XLA) has been recently identified to code for a cytoplasmic tyrosine kinase (Bruton's agammaglobulinemia tyrosine kinase, BTK), required for normal B cell development. BTK, like many other cytoplasmic
Chen, SH +11 more
core +1 more source
Late diagnosis of agammaglobulinemia in an 8-year-old boy
Pediatria i Medycyna Rodzinna, 2016 Chromosome X-linked Bruton agammaglobulinemia is classified as a primary immunodeficiency disorder. It is a genetic condition associated with a mutation in the BTK gene encoding tyrosine kinase.
Małgorzata Sopińska +4 more
doaj +1 more source
Journal of Allergy and Clinical Immunology, 2021 BACKGROUND Late-onset complications in X-linked agammaglobulinemia (XLA) are increasingly recognized. Nodular regenerative hyperplasia (NRH) has been reported in primary immunodeficiency but data in XLA are limited. OBJECTIVE To describe NRH prevalence,
C. J. Nunes-Santos +17 more
semanticscholar +1 more source
Community-acquired Acinetobacter calcoaceticus pneumonia in a patient with agammaglobulinaemia
New Microbes and New Infections, 2021 We herein describe the case of a 38-year-old patient with congenital agammaglobulinemia who presented with community-acquired pneumonia; acute respiratory failure with sepsis ensued requiring ICU admission, mechanical ventilation and vasopressors ...
K. El Gharib +3 more
doaj +1 more source