Results 1 to 10 of about 5,617 (179)

Mycoplasma pneumonia in a patient with X-linked agammaglobulinemia [PDF]

BMC Infectious Diseases
Background X-linked agammaglobulinemia (XLA), also referred to as Bruton’s tyrosine kinase deficiency, is a rare genetic disorder that affects the immune system.
Bowen Dai, Shujuan Han, Yuanfang Shen, Zhi Li, Shouhang Chen, Zhuangzhuang Wang, Yan Yuan, Ruyu Zhang, Chenyu Wang, Jiaying Zheng, Qiujing Liang, Qingmei Wang, Yaodong Zhang, Xiaolong Zhang, Fang Wang, Yuefei Jin   +15 more
doaj   +6 more sources

The dilemma of X-linked agammaglobulinemia carriers [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: Many patients with X-linked agammaglobulinemia (XLA) nowadays have reached adulthood, as well as their sisters, possibly carriers of a deleterious Bruton tyrosine kinase variant. Studies on motherhood outcomes in families with XLA are lacking.
Federica Pulvirenti, MD, PhD, Cinzia Milito, MD, PhD, Francesco Cinetto, MD, PhD, Giulia Garzi, MD, Germano Sardella, MD, Giuseppe Spadaro, MD, Francesca Lippi, MD, Valentina Guarnieri, MD, Bianca Laura Cinicola, MD, Maria Carrabba, MD, PhD, Daniele Guadagnolo, MD, Giovanna Fabio, MD, Baldassarre Martire, MD, Caterina Cancrini, MD, PhD, Giulia Lanzoni, MD, Andrea Finocchi, MD, PhD, Gigliola Di Matteo, MD, PhD, Eva Pompilii, MD, Simona Ferrari, BD, PhD, Isabella Quinti, MD, PhD   +19 more
doaj   +8 more sources

Helicobacter trogontum Bacteremia and Lower Limb Skin Lesion in a Patient with X-Linked Agammaglobulinemia—A Case Report and Review of the Literature [PDF]

Pathogens, 2022
We describe the first case of infection with Helicobacter trogontum in a patient with X-linked agammaglobulinemia. A 22-year-old male with X-linked agammaglobulinemia presented with fever, malaise and a painful skin lesion on the lower left extremity ...
Lasse Fjordside, Caroline Herløv, Camilla Heldbjerg Drabe, Leif Percival Andersen, Terese L. Katzenstein   +4 more
doaj   +4 more sources

Case report of renal manifestations in X-linked agammaglobulinemia [PDF]

Frontiers in Immunology
IntroductionX-linked agammaglobulinemia (XLA) is a humoral immunodeficiency disorder characterized by recurrent infections, severe hypogammaglobulinemia, and a deficiency of circulating B cells. While the hallmark clinical manifestations of XLA typically
Shuisen Wan, Meiling Cao, Jiahui Zou, Yaojia Bai, Mingyue Shi, Hongkun Jiang   +5 more
doaj   +4 more sources

Purulent meningitis in X-linked agammaglobulinemia: one case report [PDF]

Frontiers in Immunology
X-linked agammaglobulinemia (XLA) is characterized by a triad of primary immunodeficiency, profound hypogammaglobulinemia due to absent antibody production, and a consequent predisposition to severe and recurrent bacterial infections.
Anyi Ba, Lijiang Wang, Ruifang Ren, Ting C. Zhao, Wenyu Di, Jinggui Song   +5 more
doaj   +2 more sources

Quality of life of X-linked agammaglobulinemia patients in the United KingdomQuality of life of X-linked agammaglobulinemia patients in the United Kingdom [PDF]

Journal of Human Immunity
Assessment of UK XLA patients reveals that bronchiectasis, present in the majority of adults, is strongly associated with diminished quality of life.
Ben Shillitoe, Helen Bourne, Catherine Stroud, Terry Flood, Matthew Buckland, Winnie Ip, Austen Worth, Scott Hackett, Archana Herwadkar, Tanya Coulter, Stephen Jolles, Tomaz Garcez, Eduardo Moya, Saul N. Faust, Mark S. Pearce, Andrew R. Gennery   +15 more
doaj   +2 more sources

Autism in a Child With X-linked Agammaglobulinemia. [PDF]

Cureus, 2022
A growing evidence base has implicated immune dysfunction in the etiology of some cases of autism spectrum disorder. The precise relationship between immune disorders and autism spectrum disorder remains unclear. Herein we report a 14-year-old-male with agammaglobulinemia, who was diagnosed with autism spectrum disorder, and who has received exogenous ...
Bied A, Njuguna S, Satodiya R.
europepmc   +4 more sources

Cytomegalovirus Pneumonia in a Patient with X-Linked Agammaglobulinemia: A Case Report [PDF]

Medicina, 2022
X-linked agammaglobulinemia (XLA) is a hereditary immune disorder that predisposes patients to frequent and severe bacterial infections caused by encapsulated bacteria (such as Streptococcus pneumoniae, Staphylococcus aureus, and Haemophilus influenzae).
Yao-Xian Wong, Shyh-Dar Shyur
doaj   +2 more sources

Astrovirus Encephalitis in Boy with X-linked Agammaglobulinemia

Emerging Infectious Diseases, 2010
Encephalitis is a major cause of death worldwide. Although >100 pathogens have been identified as causative agents, the pathogen is not determined for up to 75% of cases.
Phenix-Lan Quan, Thor A. Wagner, Thomas Briese, Troy R. Torgerson, Mady Hornig, Alla Tashmukhamedova, Cadhla Firth, Gustavo Palacios, Ada Baisre-De-Leon, Christopher D. Paddock, Stephen K. Hutchison, Michael Egholm, Sherif R. Zaki, James E. Goldman, Hans D. Ochs, W. Ian Lipkin   +15 more
doaj   +5 more sources

Revisiting X-linked agammaglobulinemia. [PDF]

J Hum Immun
Discovered >70 years ago by Ogden Bruton, X-linked agammaglobulinemia (XLA), characterized by recurrent bacterial infections, hypo/agammaglobulinemia, and peripheral blood B-cell deficiency, is among the best-established inborn errors of immunity (IEIs) and one of the most well-documented single types of IEIs, the incidence of which is estimated
Kanegane H, Tanita K, Nishimura M, Tomomasa D, Inoue K, Kanamori T, Nishimura A, Ochs HD.   +7 more
europepmc   +2 more sources