Results 91 to 100 of about 587,845 (265)

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

open access: yesAdvanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou   +21 more
wiley   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

ОПРЕДЕЛЕНИЕ АНТИМИКРОБНЫХ СВОЙСТВ ЦЕФАМЕТРИНА

open access: yesВетеринарная патология, 2012
Cefametrine has marked bactericide and bacteriostatic effect on microorganisms singled out from the cow uterus at the postpartum ...

doaj  

Effect of Homogenized Callus Tissue on the Rheological and Mechanical Properties of 3D-Printed Food

open access: yesGels
The aim of the study was to develop ink enriched with a high content of lupine callus tissue (CT) suitable for 3D printing. Printable ink obtained using mashed potatoes (20 g/100 mL) and a 3% agar solution was used as the parent CT-free ink (CT0 ...
Elena Dushina   +7 more
doaj   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

open access: yesAdvanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han   +11 more
wiley   +1 more source

Effect of Deamination and Agar Addition on Physical Properties of Gelatin Extracted from Thunnus tonggol Skin [PDF]

open access: yesJournal of Food Quality and Hazards Control
Background: In the past decade, gelatin extraction from fish skin has been intensively investigated. In comparison to mammalian gelatin, fish gelatin has weaker gelatinous and rheological properties, which limits its widespread application.
F. Shakeri, Z. Bahmani, L. Mirmoghtadaie
doaj  

In-vitro gadolinium retro-microdialysis in agarose gel—a human brain phantom study

open access: yesFrontiers in Radiology
Rationale and objectivesCerebral microdialysis is a technique that enables monitoring of the neurochemistry of patients with significant acquired brain injury, such as traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH).
Chisomo Zimphango   +12 more
doaj   +1 more source

Studies on the Chemical Constitution of Agar-agar. Exhaustive Mercaptolyses of Agar-agar [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1953
Choji Araki, Susumu Hirase
openaire   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

open access: yesAdvanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi   +15 more
wiley   +1 more source

Substrate–Genotype Interaction Influences Growth and Phytochemical Composition of Wild and Commercial Purslane (Portulaca oleracea L.) Microgreens

open access: yesAgronomy
Purslane is highly suitable for intensive microgreen cultivation due to its rapid growth, high germination rate, and exceptional nutritional profile, including omega-3 fatty acids, essential vitamins, and minerals.
Ivana Kollárová   +6 more
doaj   +1 more source

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