Results 151 to 160 of about 11,914,345 (242)

INVESTIGATING THE EFFICACY OF CURCUMIN NANOEMULGEL IN COMBATING BACTERIAL ACTIVITY USING AGAR DIFFUSION METHOD AND BROTH DILUTION METHOD

Objective: The objective of this study was to develop a topical delivery formulation of curcumin nanoemulgel, evaluating its antibacterial activity against both Gram-positive and Gram-negative bacteria.
BOORAVILLI, JOSHNA, SIRISOLLA, JANAKI DEVI   +1 more
core   +1 more source

<i>In vitro</i> carbapenem activity in <i>Neisseria gonorrhoeae</i>. [PDF]

JAC Antimicrob Resist
Brousseau J, Braille A, Mainardis M, Meunier F, Mérimèche M, Caméléna F, Berçot B.   +6 more
europepmc   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Emergence of Colistin Resistance in Multidrug-Resistant Escherichia coli and Klebsiella Species From Central India: A Sentinel Study With the Detection of mcr-1 From Blood Isolates. [PDF]

Cureus
Kumari P, Seth R, Nema S.
europepmc   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Phenotypic and Genotypic Characterization of Antimicrobial Resistance in <i>Helicobacter pylori</i>: Association of <i>23S rRNA</i>, <i>gyrA</i>, and <i>rdxA</i> Gene Mutations With Resistance Patterns. [PDF]

Int J Microbiol
Makled AF, Abdelaziz HA, Allam DM, Salama MF, Khamis NN, Sleem AS.   +5 more
europepmc   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

MIC-based tuberculosis drug susceptibility testing using Sensititre MYCOTB: a diagnostic accuracy meta-analysis. [PDF]

J Clin Microbiol
D DR, G MK, Singh J, Ali S, Gaikwad S, Mohankumar T, S S, Purwar S, Biswas D, Maurya AK, Sah S, Mohanty A, Mehta R.   +12 more
europepmc   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Comparison of antimicrobial susceptibility testing of <i>Clostridium perfringens</i> by agar dilution and broth microdilution methods. [PDF]

J Vet Diagn Invest
Charlebois A, Maduro L, Boulianne M.
europepmc   +1 more source