Results 51 to 60 of about 155,399 (295)

Photo-damage, photo-protection and age-related macular degeneration [PDF]

, 2015
Age-related macular degeneration (AMD) is a degenerative retinal disease that causes blindness in people 60-65 years and older, with the highest prevalence appearing in people 90 years-old or more.
Marquioni Ramella, Melisa Daniela, Suburo, Angela Maria   +1 more
core   +1 more source

Association of sildenafil use with age-related macular degeneration: a retrospective cohort study

BMJ Open Ophthalmology
Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of ...
Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker   +6 more
doaj   +1 more source

Dual Sensory Impairment: The Correlation between Age Related Macular Degeneration and Sensorineural Hearing Loss

Medicina, 2022
The pathogeneses of age-related macular degeneration (AMD) and age-related hearing impairment are not yet fully understood. If AMD and age-related hearing impairment are correlated, the cause of both may be a result of a common vulnerability.
Marina Istrate, Mihai Hasbei-Popa, Daniela Adriana Iliescu, Ana Cristina Ghiță, Brigitha Vlaicu, Mihai Aurelian Ghiță   +5 more
doaj   +1 more source

Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]

, 2019
The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto, Greco A., La Cava M, Lambiase A, Limoli PG, Nebbioso M   +5 more
core   +1 more source

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson, Giacomo Panozzo, Giorgio Boschi, Giuseppe Scarpa, Nicola Zemella, null null, Sandro Saviano, Stefania Miotto, Stefano Piermarocchi   +8 more
core   +1 more source

Analysis of the Awareness and Access of Eye Healthcare in Underserved Populations

Vision
Introduction: Visual impairment impacts millions of people around the world, with the vast majority of problems being treatable. Disadvantaged communities are unable to utilize the same resources to treat these problems due to a lack of knowledge or ...
Karen Allison, Abdullah Virk, Asma Alamri, Deepkumar Patel   +3 more
doaj   +1 more source

The prevalence of age-related macular degeneration and osteoporosis in the older Polish population: Is there a link?

PLoS ONE, 2023
BackgroundAge-related macular degeneration is the primary cause of irreversible blindness in developed countries, whereas the global prevalence of osteoporosis-a major public health problem-is 19.7%.
Agnieszka Budnik, Marcin Palewski, Magdalena Michnowska-Kobylińska, Łukasz Lisowski, Magda Łapińska, Zofia Stachurska, Anna Szpakowicz, Jerzy Konstantynowicz, Karol Kamiński, Joanna Konopińska   +9 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration [PDF]

, 2017
10.1194/jlr.M073684Journal of Lipid Research5891785 ...
Apte, Rajendra S., Chee, Miao Ling, Cheng, Ching-Yu, Fan, Qiao, Gan, Alfred, Gemmy Cheung, Chui Ming, Khor, Chiea Chuen, Mathur, Ranjana, Tai, E. Shyong, Wong, Tien Yin, Yeo, Ian   +10 more
core   +2 more sources

Metabolomics and Age-Related Macular Degeneration

Metabolites, 2018
Age-related macular degeneration (AMD) leads to irreversible visual loss, therefore, early intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might be challenging.
Connor N. Brown, Brian D. Green, Richard B. Thompson, Anneke I. den Hollander, Imre Lengyel, on behalf of the EYE-RISK consortium   +5 more
doaj   +1 more source