Results 51 to 60 of about 207,426 (323)
EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration
International Journal of Molecular Sciences, 2020 Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT) are physiological processes required for normal embryogenesis. However, these processes can be hijacked in pathological conditions to facilitate tissue fibrosis and ...
Daisy Y. Shu +2 more
semanticscholar +1 more source
Metabolomics and Age-Related Macular Degeneration
Metabolites, 2018 Age-related macular degeneration (AMD) leads to irreversible visual loss, therefore, early intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might be challenging.
Connor N. Brown +5 more
doaj +1 more source
Journal of Ophthalmic & Vision Research, 2021 Purpose: To highlight diagnostic challenges in patients with acquired vitelliform macular degeneration (AVMD) with subretinal fluid (SRF) and to examine the characteristics of image findings in patients with AVMD.
Joseph Juliano +2 more
doaj +1 more source
Age-Related Macular Degeneration: Role of Oxidative Stress and Blood Vessels
International Journal of Molecular Sciences, 2021 Age-related macular degeneration (AMD) is a common irreversible ocular disease characterized by vision impairment among older people. Many risk factors are related to AMD and interact with each other in its pathogenesis.
Yue Ruan, Subao Jiang, A. Gericke
semanticscholar +1 more source
Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants
Advanced Functional Materials, EarlyView.Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño +5 more
wiley +1 more source
International Journal of Retina and Vitreous, 2023 Background Significant diurnal fluctuation of optical coherence tomography (OCT)-based macular fluid occurs in patients with several macular conditions including diabetic macular edema (DME) and cystoid macular edema due to retinal venous occlusion (RVO).
Blake H. Fortes +5 more
doaj +1 more source
Journal of Neuroinflammation, 2021 Age-related macular degeneration (AMD), a degenerative disease in the central macula area of the neuroretina and the supporting retinal pigment epithelium, is the most common cause of vision loss in the elderly.
K. Lee +4 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]
, 2019 The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto +5 more
core +1 more source
Acta ophthalmologica, 2021 This study aimed to determine the efficacy of a multimodal deep learning (DL) model using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) images for the assessment of choroidal neovascularization (CNV) in ...
Kai Jin +9 more
semanticscholar +1 more source