Results 31 to 40 of about 71,352 (148)

Age-Related Macular Degeneration: Classification and Pathogenesis

Türk Oftalmoloji Dergisi, 2014
Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity.
İmren Akkoyun
doaj   +1 more source

Intravitreal aflibercept in neovascular age-related macular degeneration previously treated with ranibizumab

International Journal of Ophthalmology, 2017
AIM: To report the change in visual acuity and central macular thickness (CMT) following treatment with intravitreal aflibercept injections in patients with neovascular age-related macular degeneration (nAMD) with suboptimum response to ranibizumab ...
Rachel Hui Fen Lim, Bhaskar Gupta, Peter Simcock   +2 more
doaj   +1 more source

Beyond the Complement Cascade: Insights into Systemic Immunosenescence and Inflammaging in Age-Related Macular Degeneration and Current Barriers to Treatment

Cells, 2023
Landmark genetic studies have revealed the effect of complement biology and its regulation on the pathogenesis of age-related macular degeneration (AMD).
Adnan H. Khan, Itay Chowers, Andrew J. Lotery   +2 more
doaj   +1 more source

The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration

Clinics, 2011
OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum ...
Zuhal Yildirim, Nil Irem Ucgun, Filiz Yildirim   +2 more
doaj   +1 more source

Association of sildenafil use with age-related macular degeneration: a retrospective cohort study

BMJ Open Ophthalmology
Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of ...
Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker   +6 more
doaj   +1 more source

Age-related Macular Degeneration

Ophthalmology, 1986
Age-related macular degeneration (AMD) is a major cause of visual loss. The atrophic form is more frequent but accounts for only 20% of severe visual loss. The neovascular form accounts for 80% of severe visual loss. The Macular Photocoagulation Study demonstrated that prompt argon laser photocoagulation can significantly reduce the risk of severe ...
openaire   +4 more sources

Plasma 25-Hydroxyvitamin-D (25-OHD) levels and late-stage age-related macular degeneration (AMD): Assessing the correlation

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2022
Background: Age-related Macular Degeneration (AMD) is a degenerative disease caused by multiple factors, including inflammation. This condition may lead to irreversible macular damage.
Supanji Supanji, Dewi Fathin Romdhoniyyah, Ayudha Bahana Ilham Perdamaian, Anindita Dianratri, Muhammad Bayu Sasongko, Angela Nurini Agni, Tri Wahyu Widayanti, Firman Setya Wardhana, Dian Caturini Sulistyaningrum, Mohammad Eko Prayogo, Masashi Kawaichi, Chio Oka   +11 more
doaj   +1 more source

Analysis of the Awareness and Access of Eye Healthcare in Underserved Populations

Vision
Introduction: Visual impairment impacts millions of people around the world, with the vast majority of problems being treatable. Disadvantaged communities are unable to utilize the same resources to treat these problems due to a lack of knowledge or ...
Karen Allison, Abdullah Virk, Asma Alamri, Deepkumar Patel   +3 more
doaj   +1 more source

Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid

Journal of Ophthalmic & Vision Research, 2021
Purpose: To highlight diagnostic challenges in patients with acquired vitelliform macular degeneration (AVMD) with subretinal fluid (SRF) and to examine the characteristics of image findings in patients with AVMD.
Joseph Juliano, Sagar Patel, Hossein Ameri   +2 more
doaj   +1 more source

Dual Sensory Impairment: The Correlation between Age Related Macular Degeneration and Sensorineural Hearing Loss

Medicina, 2022
The pathogeneses of age-related macular degeneration (AMD) and age-related hearing impairment are not yet fully understood. If AMD and age-related hearing impairment are correlated, the cause of both may be a result of a common vulnerability.
Marina Istrate, Mihai Hasbei-Popa, Daniela Adriana Iliescu, Ana Cristina Ghiță, Brigitha Vlaicu, Mihai Aurelian Ghiță   +5 more
doaj   +1 more source