Results 31 to 40 of about 93,339 (287)

The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration

Clinics, 2011
OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum ...
Zuhal Yildirim, Nil Irem Ucgun, Filiz Yildirim   +2 more
doaj   +1 more source

Plasma 25-Hydroxyvitamin-D (25-OHD) levels and late-stage age-related macular degeneration (AMD): Assessing the correlation

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2022
Background: Age-related Macular Degeneration (AMD) is a degenerative disease caused by multiple factors, including inflammation. This condition may lead to irreversible macular damage.
Supanji Supanji, Dewi Fathin Romdhoniyyah, Ayudha Bahana Ilham Perdamaian, Anindita Dianratri, Muhammad Bayu Sasongko, Angela Nurini Agni, Tri Wahyu Widayanti, Firman Setya Wardhana, Dian Caturini Sulistyaningrum, Mohammad Eko Prayogo, Masashi Kawaichi, Chio Oka   +11 more
doaj   +1 more source

Age-related macular degeneration in th UK [PDF]

The aim of this thesis was to investigate the prevalence and impact of age-related macular degeneration (AMD) causing visual impairment in people aged 75 years and above in the UK.
Evans, Jennifer Rosemary
core   +1 more source

Association of sildenafil use with age-related macular degeneration: a retrospective cohort study

BMJ Open Ophthalmology
Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of ...
Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker   +6 more
doaj   +1 more source

An Ecological Correlation Study of Late Age-Related Macular Degeneration and the Complement Factor H Y402H Polymorphism

, 2009
PURPOSE: To investigate whether variation in the distribution of the risk allele frequency of the Y402H single-nucleotide polymorphism (SNP) across various ethnicities and geographic regions reflects differences in the prevalence of late age-related ...
Whittaker, John C, Sofat, Reecha, Smeeth, Liam, Nonyane, Bareng A.S., Chakravarthy, Usha, Fletcher, Astrid E., Whittaker, John C., Fletcher, Astrid E, Nitsch, Dorothea, Nonyane, Bareng AS   +9 more
core   +1 more source

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD. [PDF]

, 2009
Age-related macular degeneration (AMD) is a prevalent cause of blindness in Western societies. Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly been
Weber, Bernhard H. F., Fleckenstein, Monika, Frank G Holz, Weber, B. H., Hendrik P N Scholl, Scholl, Hendrik P. N., Tim Becker, Ulrich Mansmann, Weinberger Andreas W. A., Schmitz-Valckenberg Steffen, Mackensen, F., Herold Christine, Holz, Frank G, Scholl Hendrik P. N., Weber, Bernhard H F, Andreas Mössner, Keilhauer, Claudia N, Scholl, Hendrik P N, Fritsche, Lars G., Steffen Schmitz-Valckenberg, Schmitz-Valckenberg, S., Claudia N Keilhauer, Weinberger, A. W., Fritsche, Lars G, Weinberger, Andreas W. A., Pauleikhoff, D., Becker, T., Andreas W A Weinberger, Adrion, Christine, Mansmann Ulrich, Weber Bernhard H. F., Becker Tim, Göbel, Arno, Mackensen Friederike, Holz, F. G., Monika Fleckenstein, Göbel, A., Adrion Christine, Holz Frank G., Scholl, H. P., Friederike Mackensen, Mackensen, Friederike, Mansmann, Ulrich, Göbel Arno, Becker, Tim, Fleckenstein Monika, Mössner, Andreas, Lars G Fritsche, Fritsche Lars G., Keilhauer Claudia N., Schmitz-Valckenberg, Steffen, Fritsche, L. G., Herold, Christine, Arno Göbel, Daniel Pauleikhoff, Weinberger, Andreas, Christine Herold, Mansmann, U., Christine Adrion, Bernhard H F Weber, Mössner, A., Pauleikhoff, Daniel, Keilhauer, C. N., Herold, C., Holz, Frank G., Adrion, C., Mößner Andreas, Pauleikhoff Daniel, Fleckenstein, M.   +68 more
core   +1 more source

Metabolomics and Age-Related Macular Degeneration

Metabolites, 2018
Age-related macular degeneration (AMD) leads to irreversible visual loss, therefore, early intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might be challenging.
Connor N. Brown, Brian D. Green, Richard B. Thompson, Anneke I. den Hollander, Imre Lengyel, on behalf of the EYE-RISK consortium   +5 more
doaj   +1 more source

THE CORRELATION BETWEEN AQUEOUS VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL AND CLINICAL ACTIVITY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

, 2021
Purpose: The aim of the current study was to investigate the correlation between the pretreatment aqueous level of vascular endothelial growth factor (VEGF) and clinical activity in neovascular age-related macular degeneration.Methods: Patients with ...
0000-0001-9645-3837, 10749021, 7444, SAISHIN, Yoshitsugu, 大路, 正人, SAWADA, Tomoko, OHJI, Masahito, 澤田, 修, 2767, 2502, 00378465, SAWADA, Osamu, 6625, 一山, 悠介, 90252650, 80531516, 30379193, 澤田, 智子, 7692, 西信, 良嗣, ICHIYAMA, Yusuke, 7250, 90814848, 3728, 0000-0002-9134-9886, 柿木, 雅志, 小幡, 峻平, 0000-0001-9752-0499, OBATA, Shumpei, 伊藤, 友香, 0000-0002-9828-4288, 2737, 0000-0001-6120-2392, ITO, Yuka, KAKINOKI, Masashi   +34 more
core   +1 more source

Dual Sensory Impairment: The Correlation between Age Related Macular Degeneration and Sensorineural Hearing Loss

Medicina, 2022
The pathogeneses of age-related macular degeneration (AMD) and age-related hearing impairment are not yet fully understood. If AMD and age-related hearing impairment are correlated, the cause of both may be a result of a common vulnerability.
Marina Istrate, Mihai Hasbei-Popa, Daniela Adriana Iliescu, Ana Cristina Ghiță, Brigitha Vlaicu, Mihai Aurelian Ghiță   +5 more
doaj   +1 more source

Analysis of the Awareness and Access of Eye Healthcare in Underserved Populations

Vision
Introduction: Visual impairment impacts millions of people around the world, with the vast majority of problems being treatable. Disadvantaged communities are unable to utilize the same resources to treat these problems due to a lack of knowledge or ...
Karen Allison, Abdullah Virk, Asma Alamri, Deepkumar Patel   +3 more
doaj   +1 more source