Results 31 to 40 of about 134,167 (281)

Age-Related Macular Degeneration: Classification and Pathogenesis

Türk Oftalmoloji Dergisi, 2014
Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity.
İmren Akkoyun
doaj   +1 more source

Fatores de risco para degeneração macular relacionada à idade na Argentina [PDF]

, 2013
PURPOSES: To assess the risk factors of age-related macular degeneration in Argentina using a case-control study. METHODS: Surveys were used for subjects' antioxidant intake, age/gender, race, body mass index, hypertension, diabetes (and type of ...
Carter, Marissa Janine, Eckert, Kristen Allison, Furtado, João Marcello, Lansingh, Van Charles, Luna, José Domingo, Nano, Clelia Crespo, Nano, Hugo, Nano, María Eugenia, Pighin, María Soledad, Vernengo, Luciana Fiocca, Zarate, Natalia   +10 more
core   +2 more sources

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson, Giacomo Panozzo, Giorgio Boschi, Giuseppe Scarpa, Nicola Zemella, null null, Sandro Saviano, Stefania Miotto, Stefano Piermarocchi   +8 more
core   +1 more source

Intravitreal aflibercept in neovascular age-related macular degeneration previously treated with ranibizumab

International Journal of Ophthalmology, 2017
AIM: To report the change in visual acuity and central macular thickness (CMT) following treatment with intravitreal aflibercept injections in patients with neovascular age-related macular degeneration (nAMD) with suboptimum response to ranibizumab ...
Rachel Hui Fen Lim, Bhaskar Gupta, Peter Simcock   +2 more
doaj   +1 more source

Beyond the Complement Cascade: Insights into Systemic Immunosenescence and Inflammaging in Age-Related Macular Degeneration and Current Barriers to Treatment

Cells, 2023
Landmark genetic studies have revealed the effect of complement biology and its regulation on the pathogenesis of age-related macular degeneration (AMD).
Adnan H. Khan, Itay Chowers, Andrew J. Lotery   +2 more
doaj   +1 more source

Plasma 25-Hydroxyvitamin-D (25-OHD) levels and late-stage age-related macular degeneration (AMD): Assessing the correlation

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2022
Background: Age-related Macular Degeneration (AMD) is a degenerative disease caused by multiple factors, including inflammation. This condition may lead to irreversible macular damage.
Supanji Supanji, Dewi Fathin Romdhoniyyah, Ayudha Bahana Ilham Perdamaian, Anindita Dianratri, Muhammad Bayu Sasongko, Angela Nurini Agni, Tri Wahyu Widayanti, Firman Setya Wardhana, Dian Caturini Sulistyaningrum, Mohammad Eko Prayogo, Masashi Kawaichi, Chio Oka   +11 more
doaj   +1 more source

Treatment as required versus regular monthly treatment in the management of neovascular age-related macular degeneration: a systematic review and meta-analysis [PDF]

, 2015
Background: To investigate whether treatment as required ‘pro re nata’ (PRN) versus regular monthly treatment regimens lead to differences in outcomes in neovascular age-related macular degeneration (nAMD).
Agostini, Hansjuergen, Ehlken, Christoph, Loke, Yoon K., Oeller, Patrick, Rücker, Gerta, Schmucker, Christine M., Sommer, Harriet, Virgili, Gianni   +7 more
core   +7 more sources

The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration

Clinics, 2011
OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum ...
Zuhal Yildirim, Nil Irem Ucgun, Filiz Yildirim   +2 more
doaj   +1 more source

Association of Retinal Vascular Caliber and Age-Related Macular Degeneration in Patients With the Acquired Immunodeficiency Syndrome. [PDF]

, 2018
PurposeTo evaluate the relationship between retinal vascular caliber and AMD in patients with AIDS.MethodsParticipants enrolled in the Longitudinal Study of the Ocular Complications of AIDS had retinal photographs taken at enrollment.
Danis, Ronald P, Hunt, Peter W, Jabs, Douglas A, Pak, Jeong Won, Van Natta, Mark L   +4 more
core   +1 more source

Association of sildenafil use with age-related macular degeneration: a retrospective cohort study

BMJ Open Ophthalmology
Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of ...
Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker   +6 more
doaj   +1 more source