Results 21 to 30 of about 71,352 (148)
Sleep, Pain, and Neurodegeneration: A Mendelian Randomization Study
Frontiers in Neurology, 2022 Our aim was to determine whether the genetic liability to sleep and pain-related traits have a causal effect on risk of neurodegeneration in individuals of predominantly European ancestry. We selected five neurodegenerative disorders, namely, age-related
Sandeep Grover +2 more
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PLoS ONE, 2021 ObjectiveThis study aimed to investigate the risk of Alzheimer's disease among patients with age-related macular degeneration and its association with confounding comorbidities.MethodThis was a population-based, retrospective cohort study.
Li-Yen Wen +9 more
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BMC Ophthalmology, 2023 Background The aim of this study was to describe features of disease activity in patients with treated stable macular neovascularisation (MNV) in neovascular age related macular degeneration (nAMD) using optical coherence tomography angiography (OCTA ...
Daren Hanumunthadu +6 more
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Innate immune biology in age-related macular degeneration
Frontiers in Cell and Developmental Biology, 2023 Age-related macular degeneration (AMD) is a neurodegenerative disease and a leading cause of irreversible vision loss in the developed world. While not classically described as an inflammatory disease, a growing body of evidence has implicated several ...
Karina Ascunce +4 more
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Interleukin-6 receptor blockade suppresses subretinal fibrosis in a mouse model [PDF]
International Journal of Ophthalmology, 2014 AIM:To determine the involvement of the interleukin (IL)-6 with the development of experimental subretinal fibrosis in a mouse model.METHODS:Subretinal fibrosis was induced by subretinal injection of macrophage-rich peritoneal exudate cells and the local
Wei Cui, Han Zhang, Zhe-Li Liu
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Age-Related Macular or Retinal Degeneration?
Medicina, 2023 Age-related macular degeneration (AMD) is an eye disease that leads to progressive vision loss. Its prevalence has been increasing due to population aging.
Michalina Gałuszka +2 more
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Age-related macular degeneration: an overview
Revista Brasileira de Oftalmologia, 2021 Age-related macular degeneration is the most important cause of irreversible vision loss in the elderly and has been considered a severe public health problem. Current treatments have only been successful in delaying the loss of central vision.
Rogil José de Almeida Torres +1 more
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Open innovation in neuroscience research and drug discovery
Brain and Neuroscience Advances, 2018 The pressures on the pharmaceutical industry have incentivised a number of new collaborative models of research and development which can be categorised as open innovation.
Ann J. Hunter, Wen H. Lee, Chas Bountra
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Macular Pigment Optical Density and its Determinants among Adults: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Interplay exists between the risk factors of Agerelated Macular Degeneration (AMD) and the factors influencing Macular Pigment Optical Density (MPOD) level.
POOJA GOYAL +3 more
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Age Related Macular Degeneration and Total Hip Replacement Due to Osteoarthritis or Fracture: Melbourne Collaborative Cohort Study. [PDF]
PLoS ONE, 2015 Osteoarthritis is the leading cause of total hip replacement, accounting for more than 80% of all total hip replacements. Emerging evidence suggests that osteoarthritis has a chronic inflammatory component to its pathogenesis similar to age-related ...
Elaine W Chong +8 more
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