Results 111 to 120 of about 3,959,615 (299)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Predictive role of loneliness on mortality before the age 85 years among mid- to later-life adults in the United States: a 10-year retrospective cohort study

Epidemiology and Psychiatric Sciences
Aims Loneliness is a common public health concern, particularly among mid- to later-life adults. However, its impact on early mortality (deaths occurring before reaching the oldest old age of 85 years) remains underexplored.
Hui-Ying Fan, Mu-Rui Zheng, Qinge Zhang, Sha Sha, Yuan Feng, Zhaohui Su, Teris Cheung, Gabor S Ungvari, Lloyd Balbuena, Yu-Tao Xiang   +9 more
doaj   +1 more source

Prevalence, Risk Factors and Effect of Urinary Schistosomiasis on Academic Performance of School Children Age 6-15 years in Asalaya Locality, White Nile State, Sudan 2017

, 2019
Moner Khalid Mohammed, Sayed Halaly, Heithem Awadalla, Amani Abdelrahman, Siham Ahmed Balla   +4 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Feeling good in old age: factors explaining health-related quality of life. [PDF]

Health Qual Life Outcomes, 2018
Alcañiz M, Solé-Auró A.
europepmc   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Association between age factors and strategies for promoting participation in gastric and colorectal cancer screenings. [PDF]

BMC Cancer, 2018
Hamashima C, Sano H.
europepmc   +1 more source

Risk Factors of Stunting in Children Aged 6–59 Months: A Case-Control Study in Horticulture Area

, 2022
Prayudhy Yushananta, Mei Ahyanti, Yetti Anggraini   +2 more
openalex   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Occupational factors of successful aging

International Psychogeriatrics, 2022
Pallavi, Joshi, Rajesh R, Tampi
openaire   +2 more sources