Results 111 to 120 of about 21,881,205 (365)

The effect of factors other than age upon skeletal age indicators in the adult

Annals of Human Biology, 2015
Context: Estimation of adult age from skeletal remains is problematic due to the weak and variable relationship between age indicators and age. Objectives: To assess the proportion of variation in age indicators that is associated with factors other than
S. Mays
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

The predictive value of the CONUT score combined with the A2DS2 scale for post-ischemic stroke infection [PDF]

Vojnosanitetski Pregled
Background/Aim. Stroke-associated infection is the most common and most serious complication of ischemic stroke (IS), which is the most important cause of death and disability in humans.
Zhang Yongqing, Zhang Wei, Zhou Yiwu
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

DNA methylation-based measures of biological age: meta-analysis predicting time to death

Aging, 2016
Estimates of biological age based on DNA methylation patterns, often referred to as “epigenetic age”, “DNAm age”, have been shown to be robust biomarkers of age in humans.
Brian H. Chen, R. Marioni, E. Colicino, M. Peters, C. Ward‐Caviness, P. Tsai, Nicholas S. Roetker, A. Just, E. Demerath, W. Guan, J. Bressler, M. Fornage, S. Studenski, A. Vandiver, A. Moore, Toshiko Tanaka, D. Kiel, L. Liang, P. Vokonas, J. Schwartz, K. Lunetta, J. Murabito, S. Bandinelli, D. Hernandez, D. Melzer, M. Nalls, L. Pilling, T. Price, A. Singleton, C. Gieger, R. Holle, A. Kretschmer, F. Kronenberg, Sonja Kunze, J. Linseisen, C. Meisinger, W. Rathmann, M. Waldenberger, P. Visscher, Sonia H. Shah, N. Wray, A. McRae, O. Franco, A. Hofman, A. Uitterlinden, D. Absher, T. Assimes, M. Levine, A. Lu, P. Tsao, L. Hou, J. Manson, C. Carty, A. LaCroix, A. Reiner, T. Spector, A. Feinberg, D. Levy, A. Baccarelli, J. V. van Meurs, J. Bell, A. Peters, I. Deary, J. Pankow, L. Ferrucci, S. Horvath   +65 more
semanticscholar   +1 more source

DNA Methylation Biomarkers in Aging and Age-Related Diseases

Frontiers in Genetics, 2020
Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease. It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the ...
Y. Salameh, Yosra Bejaoui, N. El Hajj
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Age is no factor in TAVI

Netherlands Heart Journal, 2022
Adrichem, R., Van Mieghem, N. M.
openaire   +3 more sources

Magneto-Convection and Lithium Age Estimates of the βPictoris Moving Group [PDF]

, 2010
Although the means of the ages of stars in young groups determined from Li depletion often agree with mean ages determined from Hertzsprung - Russell diagram isochrones, there are often statistically significant differences in the ages of individual stars determined by the two methods.
arxiv   +1 more source

Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints

Annals of the Rheumatic Diseases, 2013
Objectives Data on the incidence of symptomatic osteoarthritis (OA) are scarce. We estimated incidence of clinical hip, knee and hand OA, and studied the effect of prevalent OA on joint-specific incident OA.
D. Prieto-Alhambra, A. Judge, Muhammad Javaid, C. Cooper, A. Díez-Pérez, N. Arden   +5 more
semanticscholar   +1 more source