Results 121 to 130 of about 26,120,112 (307)
Association between age factors and strategies for promoting participation in gastric and colorectal cancer screenings. [PDF]
Hamashima C, Sano H.
europepmc +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Weight by height and age for adults, 18-74 years, United States, 1971-74 [PDF]
Age and sex distributions by weight by single inches of height for adults, 18-74 years of age in the civilian, noninstitutionalized population of the United States.Authors: Sidney Abraham, Clifford L. Johnson, and Matthew F. Najjar.DHEW publication ; no.
core
BACKGROUND: Prenatal diagnosis of trisomy 21 currently relies on assessment of risk followed by invasive testing in the 5% of pregnancies at the highest estimated risk.
Noble, P. +4 more
core +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Decomposing contribution of age and non-age factors to rapid growth of lung cancer in Xuanwei over past 30 years. [PDF]
Chen Y, Xiao Y, Yang Y, Duan J, Xu W.
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The Bronze Age climate and environment of Britain
Over the last twenty years there have been tremendous advances in our knowledge of climate change in later British prehistory from a wide variety of proxy-climate sources.
Brown, Tony
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

