Results 111 to 120 of about 26,120,112 (307)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Effects of age and illumination on night driving: a road test
, 2007 OBJECTIVE: This study investigated the effects of drivers' age and low light on speed, lane keeping, and visual recognition of typical roadway stimuli.
Wood, Joanne M. +2 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Age Standardized Rate ( ASR ) and Age Standardized Cancer Ratio ( ASCR ) of Nasopharyngeal Cancer in Kariadi Central Hospital during 2002 - 2011 [PDF]
, 2012 Background: Every year in all over the world, the incidence of nasopharyngeal carcinoma increases. In Indonesia, there was no accurate data. To get an accurate result, without using this standardization, it would be unclear if differing mortality rates ...
Puspita, M. (Merry) +3 more
core
, 2009 Background: Evidence on socioeconomic inequalities in coronary heart disease (CHD) and their pathways in the elderly is limited. Little is also known about the contributions that novel coronary risk factors (particularly inflammatory/hemostatic markers ...
Morris, RW +24 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Age and visual impairment decrease driving performance as measured on a closed-road circuit
, 2002 In this study the effects of visual impairment and age on driving were investigated and related to visual function. Participants were 139 licensed drivers (young, middle-aged, and older participants with normal vision, and older participants with ocular ...
Wood, Joanne M.
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Impact of age on functional exercise correlates in patients with advanced lung cancer
, 2014 Background: The functional exercise capacity and its correlates in advanced cancer patients in stratified age groups were examined. Materials and methods: A total of 105 patients with advanced lung cancer were recruited prospectively and stratified into
Wang, Li-Ying;Wu, Huey-Dong;Chen, Kuan-Yu;Hsieh, Chen-Hsi;Lai, Chung-Chun +1 more
core +1 more source