Results 141 to 150 of about 3,959,615 (299)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Tabagismo em adolescentes de área urbana na região Sul do Brasil

open access: yesRevista de Saúde Pública
OBJETIVO: Descrever a prevalência e os fatores de risco para o tabagismo em uma amostra de base populacional de adolescentes residentes em área urbana.
Bernardo Lessa Horta   +4 more
doaj  

Morphofunctional equivalent of skin changes in the age aspect and under the influence of exogenous factors

open access: diamond, 2022
A. G. Kvaratskheliya   +5 more
openalex   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Influence of age to the therapy and prognosis of the patients with breast cancer [PDF]

open access: yesArchive of Oncology, 2002
Gajić Zoran   +3 more
doaj   +1 more source

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