Results 211 to 220 of about 9,169,898 (343)

Atrial fibrillation and flutter in the Eastern Mediterranean: burden, disparities, and risk factor contributions from 1990 to 2021. [PDF]

Egypt Heart J
Bastan MM, Elahi Vahed I, Izadpanah K, Iranpour A, Nejadghaderi SA.   +4 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Development and validation of a risk prediction algorithm for high-risk populations combining genetic and conventional risk factors of cardiovascular disease. [PDF]

PLoS One
Puusepp T, Põld A, Milani L, Elken A, Estonian Biobank Research Team, Jürisson M, Fischer K.   +6 more
europepmc   +1 more source

Effects of Age on Fibrinolytic Activity and Factors V, VII and VIII

, 1975
Ranjan Chakrabarti, M Brozović, W. R. S. North, Yvonne Stirling, T W Meade   +4 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

The Ontogenesis of Human Fetal Hormones. IV. Somatostatin, Luteinizing Hormone Releasing Factor, and Thyrotropin Releasing Factor in Hypothalamus and Cerebral Cortex of Human Fetuses 10-22 Weeks of Age

, 1977
Michel L. Aubert, Melvin M. Grumbach, Selna L. Kaplan   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Influence of sociodemographic and clinical factors on illness progression and quality of life among older adults in Ibadan, Nigeria. [PDF]

BMC Geriatr
T Olaoluwa O, Ajayi MS.
europepmc   +1 more source

Age-related interference with Chlamydia pneumoniae microimmunofluorescence serology due to circulating rheumatoid factor [PDF]

, 1992
R P Verkooyen, M A Hazenberg, G H Van Haaren, Jules M. van den Bosch, Repke J. Snijder, H. Pieter van Helden, Henri A. Verbrugh   +6 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source