Results 61 to 70 of about 26,204,504 (362)
FEBS Letters, EarlyView.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Influence of some cardiovascular risk factors on the rela-tionship between age and blood pressure [PDF]
NORDIC BALTIC CONFERENCE ON Biomedical Engineering and Medical
Physics 2020, 2020 Blood Pressure (BP) is a biological signal related to the cardiovascular system that inevitably is affected by ageing. Moreover, it is also influenced by the presence of cardiovascular risk factors. To evaluate how the relationship be-tween BP and age changes with the presence of risk factors in hypertensive and normotensive subjects, we analyzed 880 ...
arxiv
Clinical Infectious Diseases, 2014 BACKGROUND Human immunodeficiency virus (HIV)-infected individuals may be at increased risk of age-associated noncommunicable comorbidities (AANCCs). METHODS Cross-sectional analyses of AANCC prevalence (including cardiovascular, metabolic, pulmonary ...
J. Schouten +7 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang +9 more
wiley +1 more source
Investigating the spectral age problem with powerful radio galaxies [PDF]
, 2019 The 'spectral age problem' is our systematic inability to reconcile the maximum cooling time of radiating electrons in the lobes of a radio galaxy with its age as modelled by the dynamical evolution of the lobes. While there are known uncertainties in the models that produce both age estimates, `spectral' ages are commonly underestimated relative to ...
arxiv +1 more source
Coupled Hydro-Mechanical Aging Of Short Flax Fiber Reinforced Composites [PDF]
Polymer Degradation and Stability, Elsevier, 2016, 130, pp.300 -
306, 2018 One of the challenges in the widespread use of biocomposites for engineering applications is the influence of environmental conditions on their mechanical properties, particularly for a combination of aging factors such as temperature, moisture, and mechanical stresses.
arxiv +1 more source
Reproductive Risk Factors for Breast Cancer: A Case Control Study [PDF]
, 2009 Background: Breast cancer is second most important cancer among Indian women. Although risk factors are not much prevalent as in western countries, incidence rate is increasing in India.
Hiwarkar, PA, Kulkarni, PN, Meshram, II
core
Forkhead transcription factors and ageing [PDF]
Oncogene, 2008 Mutations in single genes and environmental interventions can extend healthy lifespan in laboratory model organisms. Some of the mechanisms involved show evolutionary conservation, opening the way to using simpler invertebrates to understand human ageing.
Linda Partridge, Jens C. Brüning
openaire +2 more sources
Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors
Science, 2014 Help the Aged Muscle function declines with age, as does neurogenesis in certain brain regions. Two teams analyzed the effects of heterochronic parabiosis in mice. Sinha et al. (p.
Lida Katsimpardi +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source