Menstrual cycle patterns of college students in Gorgan-Northeast of Iran: Identify its association with sociodemographic factors [PDF]
Purpose: The menstrual cycle is used as a sign of women's health. Objective of study is determining the current menstrual patterns of students in Gorgan-Northeast of Iran, and evaluation of affecting factors on the cycle.
Gharravi, A.M.
core
The effect of factors other than age upon skeletal age indicators in the adult
Context: Estimation of adult age from skeletal remains is problematic due to the weak and variable relationship between age indicators and age. Objectives: To assess the proportion of variation in age indicators that is associated with factors other than
S. Mays
semanticscholar +1 more source
DNA Methylation Biomarkers in Aging and Age-Related Diseases
Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease. It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the ...
Y. Salameh, Yosra Bejaoui, N. El Hajj
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Detection of risk factors for obesity in early childhood with quantile regression methods for longitudinal data [PDF]
This article compares and discusses three different statistical methods for investigating risk factors for overweight and obesity in early childhood by means of the LISA study, a recent German birth cohort study with 3097 children.
Fahrmeir, Ludwig+3 more
core +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations [PDF]
© 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access.
Ernest, Terry B.+3 more
core +1 more source
DNA methylation-based measures of biological age: meta-analysis predicting time to death
Estimates of biological age based on DNA methylation patterns, often referred to as “epigenetic age”, “DNAm age”, have been shown to be robust biomarkers of age in humans.
Brian H. Chen+65 more
semanticscholar +1 more source
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet+4 more
wiley +1 more source