Results 71 to 80 of about 6,185,159 (310)

Job opportunities for people over 50 in the Netherlands

open access: yesForum Scientiae Oeconomia, 2017
Due to the effect of ageing in the labour market, there is a necessity to tackle obstacles arising from employment of older workers. The paper investigates the situation of job opportunities for people over 50 in the Netherlands. In total, 20 into-depth
Ivana Kolářová   +2 more
doaj   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Convolutional Neural Networks–Based Image Analysis for the Detection and Quantification of Neutrophil Extracellular Traps

open access: yesCells, 2020
Over a decade ago, the formation of neutrophil extracellular traps (NETs) was described as a novel mechanism employed by neutrophils to tackle infections.
Aneta Manda-Handzlik   +4 more
doaj   +1 more source

Risk Management in an Age of Change [PDF]

open access: yes
The environment in which banks and other financial services industry firms operate was once very stable. It is now increasingly permeated with change. Enhanced performance demands make this change salient to high-level decision-makers.
Daniel M.G. Raff
core  

Nitrate leaching in grazed grasslands of different composition and age [PDF]

open access: yes, 2002
In a field experiment at Research Centre Foulum a suction cup technique was used to investigate nitrate leaching from grassland depending on composition (grass-clover or perennial ryegrass), management (grazing or cutting) and age of the swards.
Eriksen, J., Vinther, F.P.
core  

In vitro study on the mechanisms of action of a novel phytotherapeutic compound against human hepatoma cells

open access: yesAnnals of Hepatology, 2007
HepG2 human hepatoma cells were incubated for 24 or 48 h with various concentrations of YHK solution. After 24 h incubation, cell proliferation and cytotoxicity were determined by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl ...
Francesco Marotta   +5 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model

open access: yesMolecular Therapy: Nucleic Acids, 2019
Alzheimer’s disease (AD) is the most common cause of dementia and cannot be cured. The etiology and pathogenesis of AD is still not fully understood, the genetics is considered to be one of the most important factors for AD onset, and the identified ...
Hui Mai   +14 more
doaj   +1 more source

A qualitative study exploring why adults with intellectual disabilities and obesity want to lose weight and views of their carers [PDF]

open access: yes, 2015
Background: Obesity is more prevalent in adults with intellectual disabilities (ID) compared to the general population. Motivations for weight loss may influence engagement with weight management programmes and have only been studied in adults without ...
Bleazard, L.   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy