Results 81 to 90 of about 32,664,496 (348)

Employees older than 50 on Croatian labour market – need for a new approach

Journal of Human Resource Management, 2017
Croatia has reached demographic maturity, with ever lower cohorts of youngers (and younger labour force numbers), longer life expectations, and rapidly growing share of older population.
Srecko Goic
doaj  

Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model

Molecular Therapy: Nucleic Acids, 2019
Alzheimer’s disease (AD) is the most common cause of dementia and cannot be cured. The etiology and pathogenesis of AD is still not fully understood, the genetics is considered to be one of the most important factors for AD onset, and the identified ...
Hui Mai, Weihao Fan, Yan Wang, Yujie Cai, Xiaohui Li, Feng Chen, Xiongjin Chen, Jingqi Yang, Pei Tang, Huiyi Chen, Ting Zou, Tingting Hong, Conghua Wan, Bin Zhao, Lili Cui   +14 more
doaj   +1 more source

Introduction - Platforms and Infrastructures in the Digital Age

Information systems research, 2018
In the last few years, leading-edge research from information systems, strategic management, and economics have separately informed our understanding of platforms and infrastructures in the digital age.
P. Constantinides, O. Henfridsson, Geoffrey G. Parker   +2 more
semanticscholar   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC).

European Heart Journal, 2014
2D : two-dimensional 99mTc-DPD : 99mTechnetium-3,3-diphosphono- 1,2-propanodi-carboxylic acid ACE : angiotensin-converting enzyme AF : atrial fibrillation AL : amyloid light chain AR : aortic regurgitation ARB : angiotensin receptor blocker ATTR ...
P. Elliott, A. Anastasakis, Michael A. Borger, M. Borggrefe, F. Cecchi, P. Charron, A. Hagège, A. Lafont, Giuseppe Limongelli, Heiko Mahrholdt, W. J. McKenna, Jens Mogensen, P. Nihoyannopoulos, Stefano Nistri, P. G. Pieper, B. Pieske, Claudio Rapezzi, Frans H. Rutten, Christoph Tillmanns, H. Watkins   +19 more
semanticscholar   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Editorial for the Special Issue: "Novel Solutions and Novel Approaches in Operational Research"

Business Systems Research
This special issue of Business Systems Research (SI of the BSR) is being co-published by the Slovenian Society INFORMATIKA – Section for Operational Research (SSI -SOR). It focuses on recent advances in Operations Research and Management Science (OR / MS)
Drobne Samo, Stirn Lidija Zadnik, Žmuk Berislav   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Age Management Practices and Benefits in Organisation: An Evaluation of the Effect of Economic Sector, Organisation Size, and Family Business Status

Business Systems Research
The ageing of the population impacts all areas and is also a challenge for human resources management. To solve this issue, age management practices are used in organisations.
Krestová Terezie, Kresta Aleš, Bestová Lucie   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source