Results 151 to 160 of about 4,208,744 (311)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Too old to choose? the effects of age and age related constructs on consumer decision making

open access: yes, 2008
Aging of societies is a major challenge to academic research as well as to management. The unstoppable trend of an aging society in most western societies offers opportunities and challenges at the same time.
Woisetschläger, David, Evanschitzky, H.
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Distributed Optimization of the Age of Information in an IoT Network with External Cooperation

open access: yes
openNelle reti IoT, garantire aggiornamenti tempestivi ed efficienti è fondamentale per ottimizzare le prestazioni dei sistemi di comunicazione.
CATANIA, DAVID EMANUELE CORRADO RAPHAEL
core  

Age of Information for Quantum Communication channels with Monogamy of Entanglement [PDF]

open access: yes
openCommunication systems play a key role in today’s society due to the enormous flow of information that we share daily in every aspect of our lives. Among others, there is a continuous flow of information regarding status updates that has to be shared ...
JABRAYILOVA, AYGUN
core  

The Role Of Technology and Innovation In The Framework Of The Information Society [PDF]

open access: yes, 2012
The literature on the information society indicates that it is a still-developing field of research. It can be explained by the lack of consensus on basic definitions and research methods.
Sasvari, Peter   +1 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Age-of-Information-Based Transmission Protocol in Vehicular Network

open access: yesEngineering Proceedings
With the development of the Internet of Things (IoT) and communication networks, the concept of a smart city emerged spontaneously. In the traffic control of a smart city, the vehicular network plays an important role.
Hung-Chin Jang, Chung-Yen Huang
doaj   +1 more source

Optimizing age of information in wireless networks with perfect channel state information

open access: yes, 2018
© 2018 IFIP. Age of information (AoI), defined as the time elapsed since the last received update was generated, is a newly proposed metric to measure the timeliness of information updates in a network.
Karaman, Sertac   +5 more
core   +1 more source

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