Results 201 to 210 of about 3,467,246 (278)

Sex Differences in Alzheimer Disease Imaging Biomarkers in a Diverse, Community-Based Cohort.

JAMA Netw Open
Akinci M, Aziz F, Palta P, Guzman D, Cheung L, Teresi JA, Brickman AM, Lao P, Luchsinger JA.   +8 more
europepmc   +1 more source

Lifecourse genome-wide association study meta-analysis refines the critical life stages for adiposity's influence on breast cancer risk. [PDF]

Sci Adv
Power GM, Bhatta L, Hughes AM, Medina-Gomez C, Richmond A, Leyden G, Lloyd-Lewis B, Sanderson E, Richmond R, Corfield EC, McCartney D, Hayward C, Fontes Marques I, Rivadeneira F, Åsvold BO, Hemani G, Felix JF, Brumpton B, Havdahl A, Davey Smith G.   +19 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Identifying the relative contributions of body size across life course to midlife and late-life cognitive function: a Bayesian analysis from the Guangzhou Biobank Cohort Study. [PDF]

J Nutr Health Aging
Hou S, Wang J, Lam TH, Cheng KK, Zhang WS, Xu L.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The Individual Relationship between Pubertal Growth and Physical Changes of Puberty in Healthy Adolescents.

Horm Res Paediatr
Yan G, Butler G, Nierop AFM, Holmgren A.
europepmc   +1 more source

Prevalence and influencing factors of perinatal depression across different stages of pregnancy and postpartum: a cross-sectional study in China. [PDF]

Front Public Health
Fu B, Zhang S, Xiang L, Cai M, Ou M, Tang G, Huang R, Lei J, Lu X.   +8 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source