Providing ambulatory healthcare for people aged 80 and over: Views and perspectives of physicians and dentists from a qualitative survey. [PDF]
PLoS One, 2022 Herrler A +4 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Geographical distribution of centenarians in Colombia: an analysis of three databases
Revista de la Facultad de Medicina, 2017 Introduction: Individuals aged one hundred years or more are of interest for the study of the aging process, which has been scarcely addressed in Colombia.
Diego Rosselli +3 more
doaj +1 more source
An overview on the treatment and outcome factors of ankle fractures in elderly men and women aged 80 and over: a systematic review. [PDF]
Arch Orthop Trauma Surg, 2022 van Halsema MS, Boers RAR, Leferink VJM.
europepmc +1 more source
No Survival Benefit in Octogenarians and Nonagenarians with Extended Hemodialysis Treatment Time. [PDF]
, 2018 BackgroundThe population of elderly end-stage renal disease patients initiating dialysis is rapidly growing. Although longer treatment is supposed to benefit for hemodialysis (HD) patients through more solute clearance and slower fluid removal, it is not
Chang, Tae Ik +8 more
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
What matters to people aged 80 and over regarding ambulatory care? A systematic review and meta-synthesis of qualitative studies. [PDF]
Eur J Ageing, 2022 Herrler A, Kukla H, Vennedey V, Stock S.
europepmc +1 more source
Development of and adherence to a gamified environment promoting health and wellbeing in older people with mild cognitive impairment [PDF]
, 2019 Overview and aims: This project aimed to promote active aging by delivering tasks via a tablet computer to participants aged 65-80 with mild cognitive impairment.
Marandure, B. N., Scase, M. O.
core
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Prevalence of household falls in long-lived adults and association with extrinsic factors
Revista Latino-Americana de Enfermagem, 2017 Resume Objective: to identify the prevalence of falls among older adults and the extrinsic factors associated with them. Method: population-based cross-sectional study with 350 older adults.
Silviane Galvan Pereira +3 more
doaj +1 more source