Results 121 to 130 of about 5,109,947 (330)

Relationship between obesity, sarcopenia, sarcopenic obesity, and bone mineral density in elderly subjects aged 80 years and over

Revista Brasileira de Ortopedia
Objective This study sought to analyze the relationship between the components and aggravations of body composition (obesity, sarcopenia, and sarcopenic obesity) and bone mineral density in elderly subjects aged ≥80 years.
Vanessa Ribeiro dos Santos, Diego Giulliano Destro Christofaro, Igor Conterato Gomes, Ismael Forte Freitas Júnior, Luís Alberto Gobbo   +4 more
doaj   +1 more source

Physical frailty prediction model for the oldest old

Revista Latino-Americana de Enfermagem, 2018
Objective: to present a physical frailty prediction model for oldest old users of primary health care, according to clinical variables. Method: cross-sectional study with proportional stratified sample of 243 oldest old subjects.
Jacy Aurelia Vieira de Sousa, Maria Helena Lenardt, Clóris Regina Blanski Grden, Luciana Kusomota, Mara Solange Gomes Dellaroza, Susanne Elero Betiolli   +5 more
doaj   +1 more source

Colonic polyp histopathology and location in a community-based sample of older adults [PDF]

, 2016
BACKGROUND: Colorectal cancer and its precursors are highly prevalent in developed countries. Estimates in the available literature for prevalence of right-sided-only lesions vary between 20.5 and 48.1 %, with association with female gender and advancing
Ade Olomu, Gurveen Chahal, Heather S. Laird-Fick, James Richard, Joseph Gardiner, Nikolay Dimitrov   +5 more
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Diagnosis and management of osteoporosis in the older senior

Clinical Interventions in Aging, 2009
Sheryl F Vondracek, Sunny A LinneburDepartment of Clinical Pharmacy, School of Pharmacy C238-L15, University of Colorado Denver, Aurora, CO, USAAbstract: The older senior is at high risk for osteoporosis.
Sheryl F Vondracek, Sunny A Linnebur
doaj  

Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study.

Age and Ageing, 2013
BACKGROUND AND AIMS sarcopenia has been indicated as a reliable marker of frailty and poor prognosis among the oldest individuals. We evaluated the impact of sarcopenia on the risk of all-cause death in a population of frail older persons living in ...
F. Landi, A. Cruz-Jentoft, R. Liperoti, A. Russo, S. Giovannini, M. Tosato, E. Capoluongo, R. Bernabei, G. Onder   +8 more
semanticscholar   +1 more source

Inception and deprescribing of statins in people aged over 80 years: cohort study [PDF]

Age and Ageing, 2017
statin use over the age of 80 years is weakly evidence-based. This study aimed to estimate rates of statin inception and deprescribing by frailty level in people aged 80 years or older.a cohort of 212,566 participants aged ≥80 years was sampled from the UK Clinical Practice Research Datalink. Statin inception was defined as a first-ever prescription in
Rathi Ravindrarajah, Judith Charlton, Martin Gulliford, Martin Gulliford, Shota Hamada, Stephen H D Jackson   +5 more
openaire   +6 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

The effects of exergaming on pain, postural control, technology acceptance and flow experience in older people with chronic musculoskeletal pain: a randomised controlled trial

BMC Sports Science, Medicine and Rehabilitation, 2020
Background Older people with chronic musculoskeletal pain are at risk of falls. This study aimed to investigate the effects of exergaming on pain and postural control in older people with chronic musculoskeletal pain.
Jae-Llane Ditchburn, Paul van Schaik, John Dixon, Alasdair MacSween, Denis Martin   +4 more
doaj   +1 more source

Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety [PDF]

, 2010
<p>Background: Melatonin is extensively used in the USA in a non-regulated manner for sleep disorders. Prolonged release melatonin (PRM) is licensed in Europe and other countries for the short term treatment of primary insomnia in patients aged 55 ...
A Brzezinski, A Chesson, AG Wade, AJ Lewy, Alan G Wade, Alex McConnachie, C Cajochen, C Liu, CA Czeisler, D Buysse, D Garfinkel, D Leger, DJ Buysse, DJ Kennaway, E Grossman, EM Gibson, G Hajak, G Mayer, Gordon Crawford, H Nakagawa, HJ Lynch, I Haimov, I Haimov, Ian Ford, IV Zhdanova, J Backhaus, JG MacFarlane, JK Wyatt, M Littner, M Littner, M Sharma, MA Hofman, MA Paul, Moshe Laudon, N Buscemi, N Zisapel, Nava Zisapel, OL Bech P, P Lemoine, P Tyrer, R Luthringer, R Mahlberg, R Mahlberg, S Ancoli-Israel, SW Lockley, T Gorfine, T Gorfine, T Roth, T Shochat, Tali Nir, W Guy, World Psychiatric Association, YH Wu   +52 more
core   +3 more sources