Results 111 to 120 of about 2,590,159 (312)

A case involving a bovine aortic arch contributing to blunt thoracic aortic injury of triple rupture close to the pericardial reflection

Trauma Case Reports
A blunt thoracic aortic injury is a fatal condition that often requires emergency surgery. Although injuries to the aortic isthmus are common in trauma patients, the proximal aortic arch often remains intact.
Takuma Aoki, Hidetoshi Oka, Naohiko Oki, Hirofumi Kasahara   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

Frontiers in Sports and Active Living
IntroductionDevelopment of accessible group exercise sessions is warranted for home-dwelling older people with cognitive impairment or dementia. This study aims to explore the experiences of participants in a group exercise session organized with ...
Kristin Taraldsen, Arnhild J. Nygård, Elisabeth Boulton, Guro Grønningsæter, Marit H. Erland, Nina Waldenstrøm, Linda Johnsen, Gro G. Tangen, Gro G. Tangen, Randi Granbo   +9 more
doaj   +1 more source

Quality of life and socio-demographic factors associated with nutritional risk in Brazilian community-dwelling individuals aged 80 and over: cluster analysis and ensemble methods. [PDF]

Front Nutr, 2023
Brech GC, da Silva VC, Alonso AC, Machado-Lima A, da Silva DF, Micillo GP, Bastos MF, de Aquino RC.   +7 more
europepmc   +1 more source

Better prepared for retirement? Using panel data to improve wealth estimates of ELSA respondents [PDF]

, 2007
We compare the key assumptions underpinning estimates of the pension wealth of ELSA respondents to outcomes over the period from 2002–03 to 2004–05. We find that many of these assumptions have, on average, proved cautious or reasonable. Improving pension
Banks, J., Emmerson, C., Tetlow, G.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analysis of Outcomes in Pancreaticoduodenectomy for Elderly Patients Aged 80 and Above: A Retrospective Study Using Inverse Probability of Treatment Weighting

Aging Medicine
Objectives With an aging population, more elderly individuals are facing the decision to undergo complex surgeries, such as pancreaticoduodenectomy (PD). This study evaluates the safety and feasibility of PD in patients aged 80 and above.
Tianxiao Wang, Yue Qiu, Yingjixing Luo, Ruili Wei, Li Xu, Jia Huang, Wenying Zhou, Hanchun Huang, Yongliang Sun, Zhiying Yang   +9 more
doaj   +1 more source

Sex differences in aged 80 and over hospitalized patients with community-acquired UTI: A prospective observational study. [PDF]

Heliyon, 2022
López-Cruz I, Esparcia A, Madrazo M, Alberola J, Eiros JM, Artero A.   +5 more
europepmc   +1 more source

Findings in young adults at colonoscopy from a hospital service database audit [PDF]

, 2017
Background: Colorectal cancer (CRC) diagnosed at
Drew, P, Hardingham, JE, Hewett, P, Lidums, I, Marker, J, Parry, S, Patel, D, Price, TJ, Roder, D, Rosty, C, Ruszkiewicz, A, Smith, E, Symonds, E, Tomita, Y, Townsend, A, Uylaki, W, Vatandoust, S, Win, AK, Wong, S, Worthley, DL, Young, GP, Young, JP   +21 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source