Results 181 to 190 of about 7,426,653 (346)

The health of Australia's males: from birth to young adulthood (0-24 years) [PDF]

SummaryThe years from birth to young adulthood (ages 0-24) encompass a breadth of life stages in which males undergo major developmental changes and acquire important social and health behaviours. In 2011, 3.7 million males (more than one-third of the

core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure. [PDF]

Asia Pac J Clin Nutr
Song S, Du H, Lu X, Luo B, Li Z.
europepmc   +1 more source

Motor unit number and transmission stability in octogenarian world class athletes: Can age-related deficits be outrun? [PDF]

, 2016
Geoffrey A. Power, Matti D. Allen, Kevin J. Gilmore, Daniel W. Stashuk, Timothy J. Doherty, Russell T. Hepple, Tanja Taivassalo, Charles L. Rice   +7 more
openalex   +1 more source

Step width variability as a discriminator of age-related gait changes [PDF]

, 2020
Ανδρέας Σκιαδόπουλος, Emily E. Moore, Harlan Sayles, Kendra K. Schmid, Nicholas Stergiou   +4 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Enhanced risk of thrombosis in aged insulin-treated diabetic rats exposed to non-severe recurrent hypoglycemia. [PDF]

Diabetol Metab Syndr
Rehni AK, Cho S, Perez-Pinzon MA, Jy W, Dave KR.   +4 more
europepmc   +1 more source

Cohort differences in cognitive aging and terminal decline in the Seattle Longitudinal Study.

, 2011
Denis Gerstorf, Nilàm Ram, Christiane A. Hoppmann, Sherry L. Willis, K. Warner Schaie   +4 more
openalex   +2 more sources

Role of lncRNAs in aging and age‐related diseases [PDF]

, 2018
Jieyu He, Chao Tu, You‐Shuo Liu
openalex   +1 more source