Results 181 to 190 of about 4,273,508 (315)

Is the association between psychological distress and risky alcohol consumption shifting over time? An age-period-cohort analysis of the Australian population

, 2023
Jillian Halladay, Tim Slade, Cath Chapman, Louise Mewton, Siobhan O’Dean, Rachel Visontay, Andrew Baillie, Maree Teesson, Matthew Sunderland   +8 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The Interrelationship of Tinnitus and Hearing Loss Secondary to Age, Noise Exposure, and Traumatic Brain Injury

, 2022
Royce E. Clifford, Allen F. Ryan, on behalf of VA Million Veteran Program   +2 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Preventable Differences in Recommended Outpatient COVID-19 Treatment Among Adults With COVID-19 in the United States. [PDF]

Med Care
Bournigal-Feliciano M, Graff N, Koumans EH, Shah MM, Woolfork MN, Lunsford NB, King H, Patel P, Hagen MB, Kappelman MD, Mayer KH, Thacker D, Arnold J, Carton TW, Draper C, Emerton D, Block J, Manns BJ, PCORnet Network Partners.   +18 more
europepmc   +1 more source

Age Integration or Age Conflict as Society Ages? [PDF]

The Gerontologist, 2000
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Neurophysiological differences between dexmedetomidine sedation and natural sleep across the rodent lifespan: implications for aging and perioperative brain health. [PDF]

Anesthesiol Perioper Sci
Siegmann MJ, Zachs DP, Kenny JD, Lark ARS, Mir FA, Melonakos ED, Hozan M, Toledano S, Goldblum RR, Liu Y, Nolan MA, Cohen G, Choi J, White CG, Crowley EA, Carpenter AH, Toro BA, Syme CE, Brown EN, Nehs CJ.   +19 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions. [PDF]

Aging Cell
Miyawaki M, Hashimoto S, Ogawa S, Kase Y.   +3 more
europepmc   +1 more source