Results 91 to 100 of about 2,584,660 (392)

Exploring an informed decision-making framework using in-home sensors: older adults’ perceptions

Journal of Innovation in Health Informatics, 2014
Background Sensor technologies are designed to assist independent living of older adults. However, it is often difficult for older adults to make an informed decision about adopting sensor technologies.Objective To explore Bruce’s framework of informed ...
Jane Chung, Blaine Reeder, Amanda Lazar, Jonathan Joe, George Demiris, Hilaire J. Thompson   +5 more
doaj   +1 more source

Patients Aged 80 Years or Older are Encountered More Potentially Inappropriate Medication Use

Chinese Medical Journal, 2016
Background:Polypharmacy and potentially inappropriate medications (PIMs) are prominent prescribing issues in elderly patients. This study was to investigate the different prevalence of PIM use in elderly inpatients between 65–79 years of age and 80 years
Li Mo, Ding Ding, S. Pu, Qin-Hui Liu, Hong Li, B. Dong, Xiaoyan Yang, Jinhan He   +7 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A systematic review of the intervention components, adherence and outcomes of enhanced recovery programmes in older patients undergoing elective colorectal surgery

BMC Geriatrics, 2019
Background Enhanced recovery programmes (ERPs) aim to attenuate the surgical stress response and accelerate recovery after surgery, but are not specifically designed for older patients.
Katleen Fagard, Albert Wolthuis, André D’Hoore, Marleen Verhaegen, Jos Tournoy, Johan Flamaing, Mieke Deschodt   +6 more
doaj   +1 more source

Effect of tobacco smoking on survival of men and women by social position: a 28 year cohort study [PDF]

, 2009
<b>Objective:</b> To assess the impact of tobacco smoking on the survival of men and women in different social positions. <b>Design:</b> A cohort observational study.
Gordon, D.S., Gruer, L., Hart, C.L., Watt, G.C.M.   +3 more
core   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Diagnosis and management of osteoporosis in the older senior

Clinical Interventions in Aging, 2009
Sheryl F Vondracek, Sunny A LinneburDepartment of Clinical Pharmacy, School of Pharmacy C238-L15, University of Colorado Denver, Aurora, CO, USAAbstract: The older senior is at high risk for osteoporosis.
Sheryl F Vondracek, Sunny A Linnebur
doaj  

Physical frailty prediction model for the oldest old

Revista Latino-Americana de Enfermagem, 2018
Objective: to present a physical frailty prediction model for oldest old users of primary health care, according to clinical variables. Method: cross-sectional study with proportional stratified sample of 243 oldest old subjects.
Jacy Aurelia Vieira de Sousa, Maria Helena Lenardt, Clóris Regina Blanski Grden, Luciana Kusomota, Mara Solange Gomes Dellaroza, Susanne Elero Betiolli   +5 more
doaj   +1 more source

APPLICABILITY OF DIET QUALITY ASSESSMENT INSTRUMENTS IN THE OLDEST-OLD: AMPAL STUDY

Geriatrics, Gerontology and Aging, 2020
OBJECTIVE: To compare the applicability of the 2006 Brazilian Ministry of Health food guide questionnaire Como ter uma alimentação saudável (QGAS — How to have a healthy diet) and the 2013 National Health Survey healthy eating questionnaire (QA-PNS) for ...
Valéria Baccarin Ianiski, Flávia Picoli Gheno, Ângelo José Gonçalves Bós   +2 more
doaj   +1 more source

Frailsafe: from conception to national breakthrough collaborative [PDF]

, 2016
The number of people aged over 60 years worldwide is projected to rise from 605 million in 2000 to almost 2 billion by 2050, while those over 80 years will quadruple to 395 million.
Downes, Tom, Gordon, Adam L., Harriman, Paul, Hopper, Adrian, Offord, Natalie, Wyrko, Zoe   +5 more
core