Results 101 to 110 of about 1,421,541 (309)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

Frontiers in Sports and Active Living
IntroductionDevelopment of accessible group exercise sessions is warranted for home-dwelling older people with cognitive impairment or dementia. This study aims to explore the experiences of participants in a group exercise session organized with ...
Kristin Taraldsen, Arnhild J. Nygård, Elisabeth Boulton, Guro Grønningsæter, Marit H. Erland, Nina Waldenstrøm, Linda Johnsen, Gro G. Tangen, Gro G. Tangen, Randi Granbo   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The impact and effectiveness of pneumococcal vaccination in Scotland for those aged 65 and over during winter 2003/2004 [PDF]

, 2008
Background: For winter 2003/2004 in Scotland, it was recommended that all those aged 65 and over be eligible to receive 23-valent polysaccharide pneumococcal vaccine (23vPPV), which has been shown to be effective in reducing the risk of invasive ...
Simpson, Colin R, Ahmed, S., Macfarlane, Tatania V., McMenamin, J., Weir, Amanda, Lewis D Ritchie, Mooney John D, McMenamin, Jim, Robertson, C., Weir, A.M., Jim McMenamin, Macfarlane, Tatania V, Ritchie Lewis D, Clarke, Stuart C., Clarke Stuart C, Simpson, Colin R., Mooney, John D., Robertson Chris, Tatania V Macfarlane, Amanda Weir, Syed Ahmed, Mooney, John D, Stuart C Clarke, Simpson, C.R., Chris Robertson, Ritchie, L.D., Mooney, J.D., Ahmed, Syed, Macfarlane Tatania V, Ritchie, Lewis D, McMenamin Jim, Weir Amanda, Clarke, Stuart C, Colin R Simpson, Clarke, S.C., Ahmed Syed, Robertson, Chris, Macfarlane, T.V., Ritchie, Lewis D., Simpson Colin R, John D Mooney, Ritchie, L.D, Macfarlane, T.V, Clarke, S.C, Weir, A, McMenamin, J, Robertson, C, Ahmed, S, Mooney, J.D, Simpson, C.R   +49 more
core   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Prevalence of household falls in long-lived adults and association with extrinsic factors

Revista Latino-Americana de Enfermagem, 2017
Resume Objective: to identify the prevalence of falls among older adults and the extrinsic factors associated with them. Method: population-based cross-sectional study with 350 older adults.
Silviane Galvan Pereira, Claudia Benedita dos Santos, Marlene Doring, Marilene Rodrigues Portella   +3 more
doaj   +1 more source

Respiratory function and its predictive value for adverse health outcomes in adults aged 80 and over

, 2017
This thesis investigates the predictive value of respiratory function for adverse health outcomes in adults aged 80 and over, the fastest growing age-group worldwide. Using the dataset of BELFRAIL, a population-based, prospective cohort of adults aged 80
Hegendörfer, Eralda
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Analysis of Outcomes in Pancreaticoduodenectomy for Elderly Patients Aged 80 and Above: A Retrospective Study Using Inverse Probability of Treatment Weighting

Aging Medicine
Objectives With an aging population, more elderly individuals are facing the decision to undergo complex surgeries, such as pancreaticoduodenectomy (PD). This study evaluates the safety and feasibility of PD in patients aged 80 and above.
Tianxiao Wang, Yue Qiu, Yingjixing Luo, Ruili Wei, Li Xu, Jia Huang, Wenying Zhou, Hanchun Huang, Yongliang Sun, Zhiying Yang   +9 more
doaj   +1 more source

Quality of life and socio-demographic factors associated with nutritional risk in Brazilian community-dwelling individuals aged 80 and over: cluster analysis and ensemble methods. [PDF]

Front Nutr, 2023
Brech GC, da Silva VC, Alonso AC, Machado-Lima A, da Silva DF, Micillo GP, Bastos MF, de Aquino RC.   +7 more
europepmc   +1 more source