Results 41 to 50 of about 1,421,541 (309)

Prevalence of potentially inappropriate medication use in older population: comparison of the Finnish Meds75+ database with eight published criteria

BMC Geriatrics, 2023
Background There are several national and international criteria available for identifying potentially inappropriate medications (PIMs) for older people. The prevalence of PIM use may vary depending on the criteria used.
Jasmin Paulamäki, Johanna Jyrkkä, Virva Hyttinen, Esa Jämsen   +3 more
doaj   +1 more source

Correlates of dyspnoea and its association with adverse outcomes in a cohort of adults aged 80 and over.

, 2017
adults aged 80 and over, a fast growing age-group, with increased co-morbidity and frailty have not been the focus of previous research on dyspnoea. We investigate the correlates of dyspnoea and its association with adverse outcomes in a cohort of adults
Hegendörfer, Eralda, Jean-Marie Degryse, Vaes, Bert, Van Pottelbergh, Gijs, Degryse, Jean-Marie, Bert Vaes, Eralda Hegendörfer, Catharina Matheï, Matheï, Catharina, Gijs Van Pottelbergh   +9 more
core   +1 more source

Inception and deprescribing of statins in people aged over 80 years: cohort study [PDF]

, 2017
Objective: Statin use over the age of 80 years is weakly evidence-based. This study aimed to estimate rates of statin inception and deprescribing by frailty level in people aged 80 years or older.
Jackson, Stephen, Hamada, Shota, Charlton, Judith Dawn, Gulliford, Martin Christopher, Shota Hamada, Judith Charlton, Rathi Ravindrarajah, Ravindrarajah, Rathi Sivagowri, Martin Gulliford, Stephen Jackson, Gulliford, Martin, Charlton, Judith, Ravindrarajah, Rathi; id_orcid   +12 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Accelerometry assessed physical activity of older adults hospitalized with acute medical illness - an observational study

BMC Geriatrics, 2020
Background In a hospital setting and among older patients, inactivity and bedrest are associated with a wide range of negative outcomes such as functional decline, increased risk of falls, longer hospitalization and institutionalization.
Plamena Tasheva, Vanessa Kraege, Peter Vollenweider, Guillaume Roulet, Marie Méan, Pedro Marques-Vidal   +5 more
doaj   +1 more source

Factors associated with improved walking in older people during hospital rehabilitation: secondary analysis of a randomized controlled trial

BMC Geriatrics, 2021
Background Older people are often admitted for rehabilitation to improve walking, yet not everyone improves. The aim of this study was to determine key factors associated with a positive response to hospital-based rehabilitation in older people.
Catherine M Said, Jennifer L McGinley, Cassandra Szoeke, Barbara Workman, Keith D. Hill, Joanne E Wittwer, Michael Woodward, Danny Liew, Leonid Churilov, Julie Bernhardt, Meg E Morris   +10 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Central nervous system relapse in patients over 80 years with diffuse large B‐cell lymphoma: an analysis of two LYSA studies

Cancer Medicine, 2018
CNS relapse is reported in 2–5% of diffuse large B‐cell lymphoma (DLBCL) patients, dramatically decreasing overall survival (OS). Very few studies address incidence and risk factors of CNS relapse in very elderly patients, a challenging population to ...
Aurélie Cabannes‐Hamy, Frederic Peyrade, Fabrice Jardin, Jean‐François Emile, Vincent Delwail, Nicolas Mounier, Corinne Haioun, Aurore Perrot, Olivier Fitoussi, Diane Lara, Richard Delarue, Marc André, Fritz Offner, Hervé Ghesquières, Laurent Pascal, Carole Soussain, Julien Lazarovici, Jean‐Marc Schiano, Philippe Gaulard, Hervé Tilly, Catherine Thieblemont, the LYSA, the lymphoma study association   +22 more
doaj   +1 more source

Use of aged care services before death [PDF]

, 2015
This bulletin examines people’s use of aged care services in the 8 years before death, using the cohort of 116,481 people who died in 2010–11 aged at least 65. Summary In 2010-11, 116,481 people died in Australia aged at least 65.
Australian Institute of Health and Welfare
core  

Univariate and multivariate analyses of prognostic factors of overall mortality in gastric cancer patients aged over 80 years.

, 2016
Univariate and multivariate analyses of prognostic factors of overall mortality in gastric cancer patients aged over 80 years.
Seungbong Han (781387), Hee Jung Park (2380813), Jin-Ho Kim (535013), Kee Wook Jung (2658472), Kee Don Choi (2658454), Ho June Song (2658475), Gin Hyug Lee (2658481), Hwoon-Yong Jung (2658466), Do Hoon Kim (2658469), Jeong Hoon Lee (821420), Ji Yong Ahn (594510)   +10 more
core   +1 more source