Results 61 to 70 of about 1,248,790 (310)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Body mass index, performance on activities of daily living and cognition: analysis in two different populations

BMC Geriatrics, 2021
Background With this study, we aim to determine the associations of the different categories of the body mass index (BMI) with activities of daily living (ADL) and cognitive performance in two different populations living in the community; Colombian and ...
Miguel Germán Borda, Luis Carlos Venegas-Sanabria, Elkin Garcia-Cifuentes, Ronald Camilo Gomez, Carlos Alberto Cano-Gutierrez, Diego Alejandro Tovar-Rios, Vera Aarsland, Khadija Khalifa, Alberto Jaramillo-Jimenez, Dag Aarsland, Hogne Soennesyn   +10 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Specificity of treatment is mandatory in very old patients with hairy cell leukemia [PDF]

Vojnosanitetski Pregled, 2015
Introduction. There are only a few available data about hairy cell leukemia (HCL) in very old patients. We presented three very different cases of HCL in very old patients diagnosed in a single center and discussed some epidemiological and ...
Marisavljević Dragomir, Marković Olivera, Živković Radmila   +2 more
doaj   +1 more source

Appropriate Medication Use in Individuals Aged 80 or More Years

, 2007
Over the last few years, there has been a rapid and steadily expanding demographic explosion in the elderly population in France. When the most dynamic segment of this growth is considered, i.e.
Yves Juillet, Thierry Marquet, Catherine Deguines   +2 more
core   +1 more source

Falls, fear of falling and related factors in community‐dwelling individuals aged 80 and over in Turkey

, 2020
Objective This study aimed to determine the prevalence of falls, fear of falling (FOF) and related factors in individuals aged 80 and over living in the Balcova district of ...
Ergor, Alp, Erdem Erkoyun, Reyhan Ucku, Alp Ergor, Ali Akoz, Ucku, Reyhan, Erkoyun, Erdem, Hatice Simsek, AKÖZ, ALİ, ŞİMŞEK KESKİN, HATİCE   +9 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Kidney Function and Cognitive Impairment in People Aged 80 Years and Over with Untreated Hypertension: A Cross-Sectional Survey

, 2016
Background/Aims: Both kidney dysfunction and cognitive impairment are common problems in hypertensive patients. However, few studies have explored the association between these conditions in hypertensive patients aged 80 or over.
Hui Jiang, Cai Lin, Tao Liu, Ying-ying Cai, Han Wang, Han-xiong Liu   +5 more
core   +1 more source

PHYSIOTHERAPY IN PERSONS OVER 80 YEARS OF AGE

, 2017
Abstract Persons older than 80 are a significant group of patients in outpatient clinics.The aim of the study was to evaluate the effect of physiotherapeutic treatment of pain experienced by geriatric patients and to evaluate the basic activities in their daily lives before and after the 10 days improvement of the elderly during ambulatory treatment ...
Szczegielniak, Jan, Bogacz, Katarzyna, Matelonek, Dagmara   +2 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source