Results 71 to 80 of about 3,754,271 (315)

Isochrone fitting in the Gaia era [PDF]

A&A 618, A54 (2018), 2018
Context. Currently galactic exploration is being revolutionized by a flow of new data: Gaia provides measurements of stellar distances and kinematics; growing numbers of spectroscopic surveys provide values of stellar atmospheric parameters and abundances of elements; and Kepler and K2 missions provide asteroseismic information for an increasing number
arxiv   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Central nervous system relapse in patients over 80 years with diffuse large B‐cell lymphoma: an analysis of two LYSA studies

Cancer Medicine, 2018
CNS relapse is reported in 2–5% of diffuse large B‐cell lymphoma (DLBCL) patients, dramatically decreasing overall survival (OS). Very few studies address incidence and risk factors of CNS relapse in very elderly patients, a challenging population to ...
Aurélie Cabannes‐Hamy, Frederic Peyrade, Fabrice Jardin, Jean‐François Emile, Vincent Delwail, Nicolas Mounier, Corinne Haioun, Aurore Perrot, Olivier Fitoussi, Diane Lara, Richard Delarue, Marc André, Fritz Offner, Hervé Ghesquières, Laurent Pascal, Carole Soussain, Julien Lazarovici, Jean‐Marc Schiano, Philippe Gaulard, Hervé Tilly, Catherine Thieblemont, the LYSA, the lymphoma study association   +22 more
doaj   +1 more source

Body mass index, performance on activities of daily living and cognition: analysis in two different populations

BMC Geriatrics, 2021
Background With this study, we aim to determine the associations of the different categories of the body mass index (BMI) with activities of daily living (ADL) and cognitive performance in two different populations living in the community; Colombian and ...
Miguel Germán Borda, Luis Carlos Venegas-Sanabria, Elkin Garcia-Cifuentes, Ronald Camilo Gomez, Carlos Alberto Cano-Gutierrez, Diego Alejandro Tovar-Rios, Vera Aarsland, Khadija Khalifa, Alberto Jaramillo-Jimenez, Dag Aarsland, Hogne Soennesyn   +10 more
doaj   +1 more source

Evolution over time of the Milky Way's disc shape [PDF]

A&A 602, A67 (2017), 2017
Context. Galactic structure studies can be used as a path to constrain the scenario of formation and evolution of our Galaxy. The dependence with the age of stellar population parameters would be linked with the history of star formation and dynamical evolution. Aims.
arxiv   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Factors associated with temporomandibular dysfunction in the elderly: an integrative literature review

Revista Brasileira de Geriatria e Gerontologia, 2019
Objective: To identify the factors associated with temporomandibular dysfunction among elderly persons. Method: An integrative literature review was carried out, evaluated by scientific publications indexed in five databases: MEDLINE/PubMed, SCOPUS, WEB
Patrícia Fernanda Faccio, Maria Angélica Bezerra dos Santos, Taís Arcanjo Maropo da Silva, Eduarda Correia Moretti, Maria das Graças Wanderley de Sales Coriolano, Carla Cabral dos Santos Accioly Lins   +5 more
doaj   +2 more sources

Specificity of treatment is mandatory in very old patients with hairy cell leukemia [PDF]

Vojnosanitetski Pregled, 2015
Introduction. There are only a few available data about hairy cell leukemia (HCL) in very old patients. We presented three very different cases of HCL in very old patients diagnosed in a single center and discussed some epidemiological and ...
Marisavljević Dragomir, Marković Olivera, Živković Radmila   +2 more
doaj   +1 more source

Thrombolysis in Patients Aged over 80 Years Is Equally Effective and Safe [PDF]

Journal of Stroke and Cerebrovascular Diseases, 2016
Despite stroke's high prevalence in the elderly, intravenous thrombolysis is licensed in Europe only for patients younger than 80 years old. We aimed to compare the functional outcomes and complication rates in patients older versus younger than 80 years old treated with intravenous thrombolysis.A retrospective observational study of patients who ...
Pego, PM, Paiva Nunes, A, Ferreira, P, Sousa, C, Amaral-Silva, A   +4 more
openaire   +4 more sources