Results 91 to 100 of about 474,048 (356)

Author Correction: Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

Nature Communications, 2021
Andrea Annibal, Rebecca George Tharyan, Maribel Fides Schonewolff, Hannah Tam, Christian Latza, Markus Max Karl Auler, Sebastian Grönke, Linda Partridge, Adam Antebi   +8 more
doaj   +1 more source

Six weeks of strength endurance training decreases circulating senescence-prone T-lymphocytes in cytomegalovirus seropositive but not seronegative older women

Immunity & Ageing, 2019
Background Ageing is associated with a decline in immune function termed immunosenescence. This process is characterized amongst others by less naive T-cells and more senescent phenotypes, which have been implicated in the pathogenesis of many age ...
Hung Cao Dinh, Ivan Bautmans, Ingo Beyer, Oscar Okwudiri Onyema, Keliane Liberman, Liza De Dobbeleer, Wim Renmans, Sam Vander Meeren, Kristin Jochmans, Andreas Delaere, Veerle Knoop, Rose Njemini   +11 more
doaj   +1 more source

Reproductive Hormone Levels Predict Changes in Frailty Status in Community-Dwelling Older Men: European Male Ageing Study Prospective Data [PDF]

, 2017
Agnieszka Święcicka, Robert J.A.H. Eendebak, Mark Lunt, Terence W O’Neill, György Bártfai, Felipe F. Casanueva, Gianni Forti, Aleksander Giwercman, Thang S. Han, Jolanta Słowikowska‐Hilczer, Michael E. J. Lean, Neil Pendleton, Margus Punab, Dirk Vanderschueren, Ilpo Huhtaniemi, Frederick C. W. Wu, Martin K. Rutter, European Male Ageing Study Group   +17 more
openalex   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Medical Risk Factors for Dementia; A Case-Control Study

Iranian Rehabilitation Journal, 2019
Objectives: Dementia is the fifth cause of death in older adults with the most significant financial, social, and caring burden on health systems across the world.
Hossein Ghasemzadeh, Ahmadali Akbari Kamrani, Yadollah Abolfathi Momtaz, Mehdi Rassafiani, Fatemeh Nourhashemi, Robab Sahaf   +5 more
doaj  

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source