Results 141 to 150 of about 474,048 (356)

Ageing and rejuvenation of tissue stem cells and their niches

Nature reviews. Molecular cell biology, 2022
A. Brunet, M. Goodell, T. Rando
semanticscholar   +1 more source

The participatory turn in Swedish ageing research: Productive interactions as learning and societal impact

, 2021
Sara Hultqvist
openalex   +1 more source

Carotid Disease and Ageing: A Literature Review on the Pathogenesis of Vascular Senescence in Older Subjects [PDF]

, 2020
Eleni Sertedaki, Dimitris Veroutis, Flora Zagouri, George Galyfos, Konstantinos Filis, Alexandros Papalambros, Konstantina Aggeli, Panagiota Tsioli, George Charalambous, George Zografos, Fragiska Sigala   +10 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Aging

Experimental Animals, 2021
openaire   +3 more sources

Author Correction: Lithocholic acid phenocopies anti-ageing effects of calorie restriction [PDF]

Qi Qu, Yan Chen, Yu Wang, Shating Long, Weiche Wang, Heng-Ye Yang, Mengqi Li, Xiao Tian, Xiaoyan Wei, Yan‐Hui Liu, Shengrong Xu, Cixiong Zhang, Mingxia Zhu, Sin Man Lam, Jianfeng Wu, Chuyu Yun, Junjie Chen, S. Xue, Baoding Zhang, Zhong-Zheng Zheng, Hai‐long Piao, Changtao Jiang, Hao Guo, Guanghou Shui, Xianming Deng, Chen‐Song Zhang, Sheng‐Cai Lin   +26 more
openalex   +1 more source

Light stabilizers added to the shell of co-extruded wood/high-density polyethylene composites to improve mechanical and anti-UV ageing properties [PDF]

, 2018
Chaozheng Liu, Changtong Mei, Bing Xu, Weimin Chen, Cheng Yong, Ke Wang, Qinglin Wu   +6 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

An aged immune system drives senescence and ageing of solid organs

Nature, 2021
Matthew J. Yousefzadeh, Rafael R. Flores, Yi Zhu, Zoe C. Schmiechen, R. W. Brooks, Christy E. Trussoni, Yuxiang Cui, Luise A Angelini, Kyoo-a Lee, S. McGowan, Adam L. Burrack, Dong Wang, Qing D Dong, A. Lu, T. Sano, Ryan D. O’Kelly, Collin A McGuckian, Jonathan I Kato, Michael P. Bank, Erin A. Wade, S. Pillai, J. Klug, W. Ladiges, C. Burd, S. Lewis, N. LaRusso, N. Vo, Yinsheng Wang, E. Kelley, J. Huard, Ingunn M. Stromnes, P. Robbins, L. Niedernhofer   +32 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source