Results 141 to 150 of about 403,137 (309)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Narratives of ageing: experiences of older women
, 2006 The aim of this research was to contribute to the growing body of academic literature regarding older women's stories of ageing. The initial impetus for the thesis came out of the disparity I observed between the way old women were often portrayed and ...
Ridley, Sally Fenwick
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Age Integration or Age Conflict as Society Ages? [PDF]
The Gerontologist, 2000 openaire +2 more sources
Immigration and growth in an ageing economy [PDF]
This paper argues that immigration can help to alleviate the burden ageing presents for the welfare states of most Western Economies. We develop a macroeconomic framework which deals with the impact of both ageing and immigration on economic growth. This
Muysken, Joan, Ziesemer, Thomas
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Sālmand, 2017 Objectives Because of increasing geriatric population in Iran, the present study aims to plan, prevent, and mitigate the complications among the retired elderly of the Tehran Municipality Pension Organization and then investigate its relation to gender ...
Helen Noei +5 more
doaj
How ageing is shaped by trade-offs [PDF]
The evolution of different life history strategies and thus different ageing patterns essentially depends on the nature of the underlying trade-offs between survival and reproduction.
Annette Baudisch
core