Results 171 to 180 of about 474,048 (356)

Restoring metabolism of myeloid cells reverses cognitive decline in ageing

Nature, 2021
Paras S. Minhas, Amira Latif‐Hernandez, Melanie R. McReynolds, A. Durairaj, Qian Wang, Amanda J. Rubin, Amit U. Joshi, J. He, E. Gauba, Ling Liu, Congcong Wang, Miles H. Linde, Y. Sugiura, P. Moon, R. Majeti, M. Suematsu, D. Mochly‐Rosen, I. Weissman, F. Longo, J. Rabinowitz, K. Andreasson   +20 more
semanticscholar   +1 more source

Revealing How Silicon Oxide Accelerates Calendar Ageing of Commercial 21700 Nickel-Rich Lithium-Ion Cells

Veronika Majherova, Eleni Fiamegkou, Puritut Nakhanivej, Gerard Bree, James Gott, Ashok S. Menon, Galo J. Páez Fajardo, Widanalage Dhammika Widanage, Alexander Dimitrijevic, Meltiani Belekoukia, Rhodri Jervis, Wesley M. Dose, Melanie Loveridge, Louis F. J. Piper   +13 more
openalex   +1 more source

Hope in an ageing Japan: transience and transcendence [PDF]

, 2016
Jason Danely
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The Impact of Societal Ageing on Individual Consumers' Insurance Purchase Intentions: A Review and Research Agenda. [PDF]

Behav Sci (Basel)
Bangaan Abdullah MH, Zheng Z, Zaki HO, Tan QL.   +3 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Autophagy, Cellular Senescence and Oxidative Stress in Ageing and Age-Related Diseases. [PDF]

Int J Mol Sci
Trachana V.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Ageing and Quality of Life in Older Adults: Updates and Perspectives of Psychosocial and Advanced Technological Interventions. [PDF]

Healthcare (Basel)
Sukenova D, Nikolic D, Izekenova A, Nurbakyt A, Izekenova A, Macijauskiene J.   +5 more
europepmc   +1 more source