From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
POPULATION AGEING AND LABOUR SUPPLY PROSPECTS IN CHINA FROM 2005 TO 2050 [PDF]
Increasing life expectancy and rapid fertility decline in China since the 1970s have accelerated the rate of population ageing, fuelling the prospects of an ageing workforce and a significant slowdown in the growth of the working age population.
Xiujian Peng, Dietrich Fausten
core
Leisure in old age: disciplinary practices surrounding the discourse of active ageing
, 2010 Jaroslava Hasmanová Marhánková
openalex +2 more sources
Evaluating the effects of population ageing on long-term growth and pension system sustainability in Bulgaria through an overlapping generations model [PDF]
, 2016 BNB, Christina Karagyozova-Markova
openalex +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Population-ageing, structural change and productivity growth [PDF]
Population-ageing is one of the traditional topics of development and growth theory and a key challenge to most modern societies. We focus on the following aspect: Population-ageing is associated with changes in demand-structure, since demand-patterns ...
Stijepic, Denis, Wagner, Helmut
core +1 more source
Stem cell dysfunction and rejuvenation strategies in ageing: emerging advances in regenerative medicine. [PDF]
Front Cell Dev BiolDinislam K +4 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Population ageing and consumption demand in Belgium [PDF]
This paper analyses the effect of population ageing on consumptions aggregates in Belgium. Since consumption expenditures change markedly over the life-cycle, the structure of aggregate consumption is likely to change in the course of population ageing ...
Mathieu Lefebvre
core