Results 211 to 220 of about 403,137 (309)

Correction to: Using scores from the 4AT delirium detection tool as an indicator of possible dementia: a study of 75 221 older adult hospital admissions. [PDF]

Age Ageing
europepmc   +1 more source

Parkinsonian signs and cognitive trajectories in older adults: a population-based longitudinal study. [PDF]

Age Ageing
Algotsson C, Overton M, Basna R, ElmstÅHl S, Siennicki-Lantz A.   +4 more
europepmc   +1 more source

The ageing process and female identity in midlife

My research examines how middle aged women (35-54 years of age) who live in the UK experience the process of growing older, and it addresses in detail the question of whether, and if so, how, their sense of self changes during midlife.
Stamou, Eva
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Ageing impacts extracellular matrix turnover and remodelling in the kidney. [PDF]

Matrix Biol Plus
Preston R, Hoyle A, Stevenson Harris A, Williams E, Birtles T, Chang J, Swift J, Eckersley A, Lennon R.   +8 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Long-term impact of a senior volunteer-driven frailty check programme on care dependency and expenditures: a 10-year population-based cohort study in Japan. [PDF]

Age Ageing
Tanaka T, Yoshizawa Y, Lyu W, Iijima K.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Frailty and intrinsic capacity: integrating complementary concepts to promote healthy ageing and transformation of care. [PDF]

Age Ageing
Cesari M, Canevelli M, Amuthavalli Thiyagarajan J, Arai H, Assantachai P, Chan P, Chhetri JK, Ferriolli E, Geffen L, Gregson CL, Guaraldi G, Gutierrez Robledo LM, Hammami S, Jang H, Kalula S, Mathur A, Merchant RA, Oliveira D, Perracini MR, Petrovic M, Polidori-Nelles MC, Rodriguez Mañas L, Rowe JW, Sabzwari S, Sadana R, Sumi Y, Tomarevska O, Vellas B, Visvanathan R, Woo J, Martin FC.   +30 more
europepmc   +1 more source