Results 241 to 250 of about 474,048 (356)

Allostatic Load, Social Participation, and Healthy Ageing: Longitudinal Evidence on the Impact of Chronic Stress. [PDF]

Geriatrics (Basel)
Sahab L, Newton JT, Sabbah W.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Epigenetic H3K4me3 activation of miR-155-5p promotes intervertebral disc degeneration via autophagy and ageing in nucleus pulposus cells. [PDF]

Noncoding RNA Res
Wang X, Sun H, Xiao W, Zhang Y, Lu X, Gong Z, Li D, Liu S, Xia X, Wang H, Shao M, Xu G, Ma X.   +12 more
europepmc   +1 more source

The role of senescent cells in ageing

Nature, 2014
J. Deursen
semanticscholar   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Understanding polysulfide evolution in wine: insights from accelerated ageing and real-time cellaring in different packaging. [PDF]

Food Chem X
Hou Y, Bekker MZ, Siebert TE, Kreitman GY, Jeffery DW.   +4 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Sex-Specific Diet-Microbiota Interactions in Ageing: Implications for Healthy Longevity. [PDF]

Nutrients
Herndez-Acosta J, Tovar AR, Torres N.
europepmc   +1 more source

Maintenance, reserve and compensation: the cognitive neuroscience of healthy ageing

Nature Reviews Neuroscience, 2018
R. Cabeza, M. Albert, S. Belleville, F. Craik, Audrey Duarte, C. Grady, U. Lindenberger, L. Nyberg, Denise C. Park, P. Reuter-Lorenz, M. Rugg, J. Steffener, M. N. Rajah   +12 more
semanticscholar   +1 more source

African Ageing Viewed Through Disability — An Analysis Using Census Data

, 2016
Reiko Hayashi
openalex   +2 more sources