Results 191 to 200 of about 52,982 (221)
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Biomolecular Markers of Brain Aging
2023Characterized by the gradual loss of physiological integrity, impaired function, and increased susceptibility to death, aging is considered the primary risk factor for major human diseases, such as cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases.
Min, Li +3 more
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Genetic Markers of Vascular Aging
Biomarkers in Medicine, 2007Age is a powerful determinant of cardiovascular risk, being associated with a number of deleterious changes in the cardiovascular system. Increased arterial stiffness is an almost ubiquitous accompaniment of aging. However, there is significant variability in age-related arterial changes between individuals likely due, in part, to genetic factors ...
Mahyar, Khaleghi, Iftikhar J, Kullo
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Markers of Early Vascular Ageing
Current Pharmaceutical Design, 2017Cardiovascular damage is clinically manifested as coronary artery disease, heart failure, stroke and peripheral artery disease. The prevalence of these adverse conditions is higher with advancing age. Although many patients present cardiovascular damage late in their life, it is common to see patients with early atherosclerosis in cardiovascular ...
Vasilios, Kotsis +3 more
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Linked markers and age at diagnosis
Genetic Epidemiology, 1997This paper examines the relationship between age at diagnosis and markers linked to a disease trait using 100 replicates from Problem 2A in Genetic Analysis Workshop 10. After establishing the relationship between age and the quantitative trait used to define affection status, Q1, we evaluated the relationship between age at diagnosis and a marker ...
T M, King, Y, Wan
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Experimental Gerontology, 1988
It is the purpose of this report to identify possible metabolic deficiencies that might serve as biochemical markers of aging. It is proposed that the multiplicity of physical and physiological changes associated with aging could be most readily explained by alterations in the regulation and/or the activities of enzymes that occupy central positions in
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It is the purpose of this report to identify possible metabolic deficiencies that might serve as biochemical markers of aging. It is proposed that the multiplicity of physical and physiological changes associated with aging could be most readily explained by alterations in the regulation and/or the activities of enzymes that occupy central positions in
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Inflammatory markers in schizophrenia in aged
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2014To identify inflammatory markers in schizophrenia in aged.The main group included 29 patients with schizophrenia, mean age 72.1 ± 6.9 years. A comparison group comprised 34 patients with Alzheimer's disease, mean age 73.4 ± 7.9 years. Seven plasma inflammatory indicators were determined.There was a significant increase in the activity/content of acute ...
L V, Androsova +4 more
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Research on Aging, 1986
From a life span perspective, aging occurs from birth to death, may involve reversible changes, and is a complex process that occurs interactively at the biological, psychosocial, and societal levels for historical cohorts. This article offers new conceptual distinctions among types of aging processes and argues for the application of specific dynamic ...
D L, Featherman, T, Petersen
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From a life span perspective, aging occurs from birth to death, may involve reversible changes, and is a complex process that occurs interactively at the biological, psychosocial, and societal levels for historical cohorts. This article offers new conceptual distinctions among types of aging processes and argues for the application of specific dynamic ...
D L, Featherman, T, Petersen
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Aging hypothesis, aging markers and the concept of biological age
Experimental Gerontology, 1988The following two points are made in this article: (1) the likely existence of more than one underlying cause of senescence strengthens the case for the development of a number of reliable markers of aging and (2) the concept of a single biological or functional age for an organism should be used with great caution, if at all.
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Constitutional genetic markers of aging
Experimental Gerontology, 1988Constitutional genetic markers of aging can be defined as members of that subset of genes that modulate the times of onset and/or the rates of progression of one or more of the processes of aging, or the response of the target cells, tissues and organisms to a particular process. These genetic factors are classified into: (1) those that control changes
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Physiological system markers of aging
Experimental Gerontology, 1988Superficially physiological measurements and processes would appear to be excellent candidates to serve as biomarkers of aging. A considered analysis reveals that the validation of them as biomarkers of aging is difficult. The available evidence indicates that the concept of physiological age does not appear to be of much value.
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