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THE CROSSLINKAGE THEORY OF AGING
Journal of the American Geriatrics Society, 1968Abstract: For many decades the theory and practice of cross‐linking (bonding that ties two or more large molecules together side to side) have been developed in industry, but only since the 1940's has the theory been considered in the field of medicine as a primary reaction underlying age‐dependent changes.
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2017
Several theories have sought to explain aging, here precisely defined as “increasing mortality with increasing chronological age in populations in the wild”. They all fall within one of two opposite and incompatible paradigms. For the first (“old paradigm”), aging is the result of degenerative phenomena that natural selection cannot counteract ...
Libertini G., Rengo G., Ferrara N.
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Several theories have sought to explain aging, here precisely defined as “increasing mortality with increasing chronological age in populations in the wild”. They all fall within one of two opposite and incompatible paradigms. For the first (“old paradigm”), aging is the result of degenerative phenomena that natural selection cannot counteract ...
Libertini G., Rengo G., Ferrara N.
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THE CYBERNETIC THEORY OF AGING
Journal of the American Geriatrics Society, 1969A bstract An outline is given of the basic facts that the cybernetic theory of aging attempts to harmonize. An experiment is cited which adds substantially to support of the theory. The theory is described and its relation to Bjorksten's crosslinkage theory indicated.
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Annals of the New York Academy of Sciences, 1998
ABSTRACT: Aging is the accumulation of diverse adverse changes that increase the risk of death. These changes can be attributed to development, genetic defects, the environment, disease, and the inborn aging process. The chance of death at a given age serves as a measure of the number of accumulated aging changes, that is, of physiologic age, and the ...
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ABSTRACT: Aging is the accumulation of diverse adverse changes that increase the risk of death. These changes can be attributed to development, genetic defects, the environment, disease, and the inborn aging process. The chance of death at a given age serves as a measure of the number of accumulated aging changes, that is, of physiologic age, and the ...
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Theory of Aging and Cognitive Theory of Personality
Human Development, 2009Findings from different approaches to gerontology were evaluated in terms of cognitive theory of personality. Contributions of this theory to the theory of aging are demonstrated by formulating three postulates referring to the relationship between objective situational change, perceived change, motivational change, behavioral change, and adjustment to
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Current Theories of Biological Aging
The Gerontologist, 1974Several lines of evidence have led to the notion that biological aging occurs as a result of changes in the information-containing molecules either at the genetic or epigenetic level. The error theory, the redundant message theory, the codon restriction theory, and the transcriptional event theory represent the major current conceptualizations of ...
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The Free-Radical Theory of Aging
Antioxidants & Redox Signaling, 1982Aging is the accumulation of changes that increase the risk of death. Aging changes can be attributed to development, genetic defects, the environment, disease, and an inborn process: the aging process. The latter is the major risk factor for disease and death after age 28 in the developed countries.
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Mutation Research/DNAging, 1992
Free radical reactions are ubiquitous in living things. Studies on the origin and evolution of life provide a reasonable explanation for the prominent presence of this unruly class of chemical reactions. These reactions have been implicated in aging.
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Free radical reactions are ubiquitous in living things. Studies on the origin and evolution of life provide a reasonable explanation for the prominent presence of this unruly class of chemical reactions. These reactions have been implicated in aging.
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