Results 121 to 130 of about 5,082,581 (316)

The Legislative History of the Administrative Procedure Act [PDF]

, 2016
During the twentieth century, one of the most important developments in American government and politics was the expanding power of administrative agencies of all kinds.
Elias, Roni
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Sense of agency in gesture-based interactions: modulated by sensory modality but not feedback meaning

Frontiers in Computer Science
IntroductionGesture-based interactions provide control over a system without the need for physical contact. Mid-air haptic technology allows a user to not visually engage with the interface while receiving system information and is readily manipulable ...
George Evangelou, Orestis Georgiou, Eddie Brown, James W. Moore   +3 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The Case for Asymmetry in Online Research: Caring About Issues in Australian and Canadian Web 1.0 Bee Networks

International Journal of Communication, 2020
We critically engage with the actor–network theory precept that human and nonhuman actants have symmetrical capacities. In contrast, we distinguish actor-actants, who have the capacity to care about other actants, from issue-actants, who do not.
Mathieu O'Neil, Mahin Raissi, Bethaney Turner   +2 more
doaj  

Regional Growth Paths: From Structure to Agency and Back

, 2018
Markus Grillitsch, Markku Sotarauta
openalex   +1 more source

The Consumer Financial Protection Agency [PDF]

, 2009
Examines the current regulatory structures for consumer financial services protection, its limitations, and concerns about the proposal to consolidate consumer protection functions under one agency with research, rule-making, and enforcement ...
Adam J. Levitin
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Minimum levels of performance and notices to improve: guidance applying to the 2011/12 academic year [PDF]

, 2010
"This document sets out how the Skills Funding Agency and the Young People’s Learning Agency (YPLA) intend to approach identified provider underperformance in the 2011/12 academic year in respect of: financial health and financial management and ...

core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source