Results 81 to 90 of about 973,251 (318)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Editorial: ‘Inter-identities' in Life, Mind, and Society

open access: yesFrontiers in Psychology, 2021
Arantza Etxeberria   +3 more
doaj   +1 more source

Photo-ethnography by People Living in Poverty Near the Northern Border of Mexico

open access: yesForum: Qualitative Social Research, 2009
People living in poverty have had little opportunity to express their feelings about the precarious situation in which they live. Most studies on poverty have focused on describing its most prominent characteristics, more often in a quantitative manner ...
Jesús René Luna Hernández
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

L’agentivité des jeunes exposés à la violence conjugale soutenue par la méthode du calendrier historique de vie

open access: yesEnfances, Familles, Générations, 2022
Research framework: This article is based on two studies of young adults who were exposed to intimate partner violence (IPV) in childhood or adolescence. These studies focused on their life course and their views of intimate partner violence. Objectives:
Annie Dumont   +4 more
doaj  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Review: David Howarth (2000). Discourse

open access: yesForum: Qualitative Social Research, 2002
HOWARTH's book is an accessible, readable and concise overview of theories of and approaches to discourse in the human and social sciences, focusing upon LACLAU and MOUFFE's discourse theory approach.
John Cromby
doaj  

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