Results 91 to 100 of about 11,927,890 (342)

Agent-Based Model of Genotype Editing

Evolutionary Computation, 2007
Evolutionary algorithms rarely deal with ontogenetic, non-inherited alteration of genetic information because they are based on a direct genotype-phenotype mapping. In contrast, several processes have been discovered in nature which alter genetic information encoded in DNA before it is translated into amino-acid chains. Ontogenetically altered genetic
Chien-Feng Huang, Jasleen Kaur 0002, Ana Gabriela Maguitman, Luis M. Rocha   +3 more
openaire   +4 more sources

Which Sensitivity Analysis Method Should I Use for My Agent-Based Model?

Journal of Artificial Societies and Social Simulation, 2016
Existing methodologies of sensitivity analysis may be insufficient for a proper analysis of Agent-based Models (ABMs). Most ABMs consist of multiple levels, contain various nonlinear interactions, and display emergent behaviour.
G. T. Broeke, G. Voorn, A. Ligtenberg
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Coupling environmental, social and economic models to understand land-use change dynamics in the Mekong Delta

Frontiers in Environmental Science, 2016
The Vietnamese Mekong Delta has undergone in recent years a considerable transformation in agricultural land-use, fueled by a boom of the exportation, an increase of population, a focus on intensive crops, but also environmental factors like sea level ...
Alexis eDrogoul, Nghi Quang Huynh, Nghi Quang Huynh, Quang Chi Truong, Quang Chi Truong   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Game Theoretic Analysis of the Feedback Loop Caused by Widely Available Computer Estimation on Market Values

Proceedings of the International Florida Artificial Intelligence Research Society Conference
Public availability of computer generated predictions can change the markets and its impact is here investigated with a game theoretic approach. Real estate inflation is not a new phenomenon but its consistent and almost monotonous persistence over ...
Viorel Silaghi, Zobaida Alssadi, Ben Mathew, Majed Alotaibi, Ali Alqarni, Marius Silaghi   +5 more
doaj   +1 more source

An agent-based model of anoikis in the colon crypt displays novel emergent behaviour consistent with biological observations [PDF]

Royal Society Open Science, 2017
Colorectal cancer (CRC) is a major cause of cancer mortality. Colon crypts are multi-cellular flask-shaped invaginations of the colonic epithelium, with stem cells at their base which support the continual turnover of the epithelium with loss of cells by
Tim Ingham-Dempster, Dawn C. Walker, Bernard M. Corfe   +2 more
doaj   +1 more source

Rock around the clock: An agent-based model of low- and high-frequency trading [PDF]

Journal of evolutionary economics, 2014
We build an agent-based model to study how the interplay between low- and high-frequency trading affects asset price dynamics. Our main goal is to investigate whether high-frequency trading exacerbates market volatility and generates flash crashes.
Sandrine Jacob Leal, M. Napoletano, A. Roventini, G. Fagiolo   +3 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source