Results 91 to 100 of about 32,725,060 (295)

Creating and Validating Hybrid Large-Scale, Multi-Modal Traffic Simulations for Efficient Transport Planning

Smart Cities
Mobility digital twins (MDTs), which utilize multi-modal microscopic (micro) traffic simulations and an activity-based demand generation, are envisioned as flexible and reliable planning tools for addressing today’s increasingly complex and diverse ...
Fabian Schuhmann, Ngoc An Nguyen, Jörg Schweizer, Wei-Chieh Huang, Markus Lienkamp   +4 more
doaj   +1 more source

Transportation in Agent-Based Urban Modelling [PDF]

, 2017
As the urban population rapidly increases to the point where most of us will be living in cities by the end of this century, the need to better understand urban areas grows ever more urgent. Urban simulation modelling as a field has developed in response to this need, utilising developing technologies to explore the complex interdependencies, feedbacks,
Sarah Wise, Andrew T. Crooks, Michael Batty   +2 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Unraveling the Phenomenon of Supply‐Demand Feedback in Agricultural Water Interventions

Earth's Future
The Agricultural water interventions can trigger human‐water feedback, including unintended supply demand feedback—where increased water availability drives greater water use. In the Kamadhiya catchment, India, the introduction of check dams (CDs) led to
Mohammad Faiz Alam, Michael E. McClain, Alok Sikka, D. R. Sena, Saket Pande   +4 more
doaj   +1 more source

Workshop on Agent-Based Modeling [PDF]

, 2007
After the success of the first workshop of Agent-based approach in Economic and Social Complex Systems (AESCS) in Shimane, 2001, we have held a similar workshop in Niigata, 2003. The title is International Workshop on Agent-Based Modeling. The aims and scope are summarized as follows: Agent-Based Modeling has become one of major techniques to design ...
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Agent-based formation of virtual organisations

, 2004
Virtual organisations (VOs) are composed of a number of individuals, departments or organisations each of which has a range of capabilities and resources at their disposal. These VOs are formed so that resources may be pooled and services combined with a
Preece, A., Fiddian, Nicholas John, Luck, M, Luck, Michael; id_orcid, Nguyen, Thuc Duong, Nguyen, Thuc D., Nguyen, T.D., Chalmers, S, Preece, A, Luck, Michael, Deora, Vikas, Jennings, N. R., Fiddian, N., Jennings, NR, Gray, A, Norman, Timothy, Preece, Alun D., Dang, Viet D., Dang, V.D., Fiddian, Nick J., Preece, Alun David, Deora, V., Norman, Timothy J., Shao, Jianhua, Gray, William Alexander, Fiddian, N, Dang, Viet Dung, Deora, V, Gray, W. Alex, Nguyen, TD, Chalmers, Stuart, Jennings, N.R., Norman, TJ, Shao, J, Jennings, Nicholas R., Chalmers, S., Gray, A., Dang, VD, Shao, J., Luck, M.   +39 more
core   +1 more source

Representation of unlearning in the innovation systems: A proposal from agent-based modeling

Estudios Gerenciales, 2017
In the present work it is understood the unlearning as the voluntary effort made by firms to abandon the capacities that are not necessary to compete in an innovation system. Modeling and simulating unlearning makes it possible to know emerging behaviors
Santiago Quintero Ramírez, Walter Lugo Ruiz Castañeda, Jorge Robledo Velásquez   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source