Results 91 to 100 of about 831,996 (266)
HMAE: a high-fidelity multi-agent simulator for economic phenomenon emergence
Frontiers in PhysicsEconomic models based on multi-agents are increasingly attracting attention and can provide a new perspective for exploring the causes behind social phenomena at the individual level.
Chao Wang +6 more
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A multi-scale fine-grained LUTI model to simulate land use scenarios in Luxembourg
Journal of Transport and Land Use, 2018 The increasing attractiveness of Luxembourg as a place to work and live puts its land use and transport systems under high pressure. Understanding how the country can accommodate residential growth and additional traffic in a sustainable manner is a key
Philippe Gerber +3 more
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An Agent-based Model for the Humanities
Digital Humanities Quarterly, 2013 The Humanities now confront a new era in cultural representations — the digital age. As a consequence, our approach to culture may be modified because technology allows us to now visualize our thoughts and theories using digital and computing techniques.
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
On the Limits of Agency in Agent-based Models
International Joint Conference on Autonomous Agents and Multiagent SystemsAgent-based modeling (ABM) offers powerful insights into complex systems, but its practical utility has been limited by computational constraints and simplistic agent behaviors, especially when simulating large populations. Recent advancements in large language models (LLMs) could enhance ABMs with adaptive agents, but their integration into large ...
Ayush Chopra +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Towards agent-based-model informed neural networks
EPJ Data ScienceIn this article, we present a framework for designing neural networks that remain consistent with the underlying principles of agent-based models. We begin by highlighting the limitations of standard neural differential equations in modeling complex ...
Nino Antulov-Fantulin
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source