Results 101 to 110 of about 11,927,890 (342)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
An Agent-based Route Choice Model [PDF]
Travel demand emerges from individual decisions. These decisions, depending on individual objectives, preferences, experiences and spatial knowledge about travel, are both heterogeneous and evolutionary. Research emerging from fields such as road pricing
David Levinson, Lei Zhang, Shanjiang Zhu
core
A Methodology to Engineer and Validate Dynamic Multi-level Multi-agent Based Simulations
, 2013 This article proposes a methodology to model and simulate complex systems, based on IRM4MLS, a generic agent-based meta-model able to deal with multi-level systems.
C. Chen +9 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Ecological Solutions and EvidenceHoneybees are important pollinators for many agricultural food crops, and it is critical that the response of honeybee colonies to pesticides be included in pesticide risk assessments.
Daniel Dawson +2 more
doaj +1 more source
Quantifying age-specific household contacts in Aotearoa New Zealand for infectious disease modelling
Royal Society Open ScienceAccounting for population age structure and age-specific contact patterns is crucial for accurate modelling of human infectious disease dynamics and impact.
Caleb Sullivan +2 more
doaj +1 more source
Agent Based Model to Estimate Time to Restoration of Storm-Induced Power Outages
Infrastructures, 2018 Extreme weather can cause severe damage and widespread power outages across utility service areas. The restoration process can be long and costly and emergency managers may have limited computational resources to optimize the restoration process.
Tara Walsh +3 more
doaj +1 more source
An Agent-Based Approach to Immune Modelling [PDF]
, 2006 This study focuses on trying to understand why the range of experience with respect to HIV infection is so diverse, especially as regards to the latency period. The challenge is to determine what assumptions can be made about the nature of the experience of antigenic invasion and diversity that can be modelled, tested and argued plausibly.
Perrin, Dimitri +3 more
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Introducing Preference Heterogeneity into a Monocentric Urban Model: an Agent-Based Land Market Model [PDF]
, 2008 This paper presents an agent-based urban land market model. We first replace the centralized price determination mechanism of the monocentric urban market model with a series of bilateral trades distributed in space and time.
Filatova, Tatiana +2 more
core +1 more source