Results 111 to 120 of about 459,186 (346)
The Lancet Regional Health. AmericasSummary: Background: The current recommendation for MenACWY vaccination against invasive meningococcal disease (IMD) in the United States (US) includes two doses: the first dose at ages 11–12 and a booster dose at age 16.
Affan Shoukat +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Simulating Port Expansion Plans using Agent based Modelling
International Journal of Technology, 2015 Jakarta International Container Terminal (JICT), which is the main international port of Indonesia, is overcrowded and is going to be expanded.
Ramadhianto Agung Wibowo +3 more
doaj +1 more source
Argumentative agent-based models
Journal of Applied Logics - IfCoLog Journal of Logics and their ApplicationsSummary: Communication plays a pivotal role in social phenomena such as belief polarization, scientific inquiry, and collective problem-solving. Agent-Based Models (ABMs) are computational tools that simulate the emergence of macro-level phenomena from micro-level interactions among agents. This paper focuses on Argumentative Agent-Based Models (AABMs),
Dupuis de Tarlé, Louise +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Generating a synthetic population in support of agent-based modeling of transportation in Sydney [PDF]
, 2013 The complexity of large cities such as Sydney makes planning challenging. There is a growing need for new and evolving tools to assist research and decision-making.
Barthelemy, J. +5 more
core
, 2014 Individual-based hybrid modelling of spatially distributed systems is usually expensive. Here, we consider a hybrid system in which mobile agents spread over the space and interact with each other when in close proximity.
Feng, Cheng
core +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Reviewing agent-based modelling of socio-ecosystems: a methodology for the analysis of climate change adaptation and sustainability [PDF]
The integrated - environmental, economic and social - analysis of climate change calls for a paradigm shift as it is fundamentally a problem of complex, bottom-up and multi-agent human behaviour.
Carlo Giupponi, Stefano Balbi
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source