Results 151 to 160 of about 47,987 (262)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Agent-based modelling reveals feedback loops and non-linearity between mating system evolution and disease dynamics. [PDF]

PLoS One
Tarantino R, Garcia-Gonzalez F.
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Discrete event simulation and agent-based modelling of distributed situation awareness in patient flow management. [PDF]

Sci Rep
Alhaider AA, Lau N, Alotaik O, Davenport PB.   +3 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Comparison of residential and mobility-integrated air pollution exposures from tracking campaigns and agent-based modelling in Switzerland and the Netherlands. [PDF]

J Expo Sci Environ Epidemiol
de Hoogh K, Flückiger B, Probst-Hensch N, Jeong A, Imboden M, Karsies A, Schmitz O, Vermeulen R, Kyriakou K, Ndiaye A, Shen Y, Karssenberg D, Vienneau D, Hoek G.   +13 more
europepmc   +1 more source

Agent-based modelling of reactive vaccination of workplaces and schools against COVID-19. [PDF]

Nat Commun, 2022
Faucher B, Assab R, Roux J, Levy-Bruhl D, Tran Kiem C, Cauchemez S, Zanetti L, Colizza V, Boëlle PY, Poletto C.   +9 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

BharatSim: An agent-based modelling framework for India. [PDF]

PLoS Comput Biol
Cherian P, Kshirsagar J, Neekhra B, Deshkar G, Hayatnagarkar H, Kapoor K, Kaski C, Kathar G, Khandekar S, Mookherjee S, Ninawe P, Noronha RF, Ranka P, Sinha V, Vinod T, Yadav C, Gupta D, Menon GI.   +17 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source