Covid-19 in hospitals: Studying influencing factors through agent-based modelling. [PDF]
Michaelides P, Sarkadi Ş.
europepmc +1 more source
Agent-based modelling of complex factors impacting malaria prevalence. [PDF]
Amadi M, Shcherbacheva A, Haario H.
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Agent-based modelling of the early stages of actin polymerisation required to drive endocytosis in Saccharomyces cerevisiae. [PDF]
Hancock LP +4 more
europepmc +1 more source
The Impact of Blockchain Application on the Qualification Rate and Circulation Efficiency of Agricultural Products: A Simulation Analysis with Agent-Based Modelling. [PDF]
Wang L, Qi C, Jiang P, Xiang S.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Agent based modelling of blood borne viruses: a scoping review. [PDF]
Ale S, Hunter E, Kelleher JD.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Agent-based modelling of Mycobacterium tuberculosis transmission: a systematic review. [PDF]
Bui VL +6 more
europepmc +1 more source

