Results 31 to 40 of about 22,532 (261)

Cooperative behavior in pre-state societies: an agent based approach to the Axum civilization

open access: yesFrontiers in Complex Systems
IntroductionThis study intends to test the hypothesis that, contrary to traditional interpretation, the social structure of the polity of Aksum–especially in its early stages–was not characterized by a vertical hierarchy with highly centralized ...
Riccardo Vasellini   +6 more
doaj   +1 more source

Going beyond BDI for agent-based simulation

open access: yesJournal of Information and Telecommunication, 2019
Research in multi-agent systems has resulted in agent programming languages and logics that are used as a foundation for engineering multi-agent systems.
John Bruntse Larsen
doaj   +1 more source

Functional balance at rest of hemispheric homologs assessed via normalized compression distance

open access: yesFrontiers in Neuroscience
IntroductionThe formation and functioning of neural networks hinge critically on the balance between structurally homologous areas in the hemispheres. This balance, reflecting their physiological relationship, is fundamental for learning processes.
Annalisa Pascarella   +12 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Novice, the Expert, and the Algorithm: A Comparative Analysis of Human Expertise Transfer and AI Performance in Audio-Only Gaming Environments

open access: yesApplied Sciences
This study provides a symmetrical, cross-genre comparison of human expertise transfer and “blind” artificial intelligence (AI) performance in audio-only gaming environments.
Ibrahim Khan   +3 more
doaj   +1 more source

On Agent-Based Modelling and Computational Social Science

open access: yesFrontiers in Psychology, 2014
In the first part of the paper, the field of Agent-Based Modelling is discussed focusing on the role of generative theories, aiming at explaining phenomena by growing them.
Rosaria eConte, Mario ePaolucci
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

AN INTRODUCTION TO AGENT BASED MODELLING AND SIMULATION OF SOCIAL PROCESSES [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2003
The paper provides an introduction to agent-based modelling and simulation of social processes. Reader is introduced to the worldview underlying agent-based models, some basic terminology, basic properties of agent-based models, as well as to what one ...
Ognjen Skunca, Armano Srbljinovic
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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