Results 81 to 90 of about 2,509,130 (293)
Unraveling the Phenomenon of Supply‐Demand Feedback in Agricultural Water Interventions
Earth's FutureThe Agricultural water interventions can trigger human‐water feedback, including unintended supply demand feedback—where increased water availability drives greater water use. In the Kamadhiya catchment, India, the introduction of check dams (CDs) led to
Mohammad Faiz Alam +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Introducing Preference Heterogeneity into a Monocentric Urban Model: an Agent-Based Land Market Model [PDF]
, 2008 This paper presents an agent-based urban land market model. We first replace the centralized price determination mechanism of the monocentric urban market model with a series of bilateral trades distributed in space and time.
Filatova, Tatiana +2 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Bottom-up ecology: an agent-based model on the interactions between competition and predation
Letters in Biomathematics, 2016 We developed an agent-based computer model of an ecosystem to predict interactions of competition and predation. In our simulations of the model, the effects of the ‘Gause law’ emerged as the results of population fluctuations and a large number of ...
Istvan Karsai +2 more
doaj +1 more source
The Spatial Agent-based Competition Model (SpAbCoM) [PDF]
The paper presents a detailed documentation of the underlying concepts and methods of the Spatial Agent-based Competition Model (SpAbCoM). For instance, SpAbCoM is used to study firms' choices of spatial pricing policy (GRAUBNER et al., 2011a) or pricing
Graupner, Marten
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Multi-level agent-based modeling with the Influence Reaction principle
, 2012 This paper deals with the specification and the implementation of multi-level agent-based models, using a formal model, IRM4MLS (an Influence Reaction Model for Multi-Level Simulation), based on the Influence Reaction principle.
Jolly, Daniel, Morvan, Gildas
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source