A critical review of the epidemiology of Agent Orange/TCDD and prostate cancer. [PDF]
Eur J Epidemiol, 2014 To inform risk assessment and regulatory decision-making, the relationship between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and prostate cancer requires clarification. This article systematically and critically reviews the epidemiologic evidence on the
Chang ET +4 more
europepmc +6 more sources
Agent Orange Causes Metabolic Dysfunction and Molecular Pathology Reminiscent of Alzheimer’s Disease [PDF]
Journal of Alzheimer's Disease Reports, 2023 Background: Agent Orange, an herbicide used during the Vietnam War, contains 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T).
Suzanne M. de la Monte +3 more
doaj +2 more sources
Agent orange exposure and prostate cancer risk in the million veteran program [PDF]
Acta OncologicaBackground: The US government considers veterans to have been exposed to Agent Orange if they served in Vietnam while the carcinogen was in use, and these veterans are often deemed at high risk of prostate cancer (PCa).
Meghana S. Pagadala +14 more
doaj +2 more sources
Agent Orange and head and neck cancer: A systematic review and meta‐analysis [PDF]
World Journal of Otorhinolaryngology-Head and Neck SurgeryObjective To assess the incidence of head and neck cancer in patients exposed to Agent Orange and related dioxins. Methods Studies were identified through CINAHL, PubMed, and Scopus. Primary studies were identified through April 2023.
Neil P. Monaghan +5 more
doaj +2 more sources
AGENT ORANGE‐INDUCED Anaplastic Large‐Cell Lymphoma (ALCL) with Cutaneous Involvement [PDF]
Clinical Case Reports, 2021 Anaplastic large‐cell lymphoma (ALCL) is a CD30 + lymphoproliferative disorder that may manifest with skin involvement.1 We present a rare case of Agent Orange‐induced ALCL with cutaneous involvement of the hand, surgical excision, and follow‐up ...
Morgan Lorio +3 more
doaj +2 more sources
Association of UGT1A1 gene variants, expression levels, and enzyme concentrations with 2,3,7,8-TCDD exposure in individuals exposed to Agent Orange/Dioxin [PDF]
Scientific ReportsAmong the congener of dioxin, 2,3,7,8-TCDD is the most toxic, having a serious long-term impact on the environment and human health. UDP-glucuronosyltransferase 1A1 (UGT1A1) plays a crucial role in the detoxification and excretion of endogenous and ...
Ha Van Quang +4 more
doaj +2 more sources
Serum dioxin and DNA methylation in the sperm of operation ranch hand veterans exposed to Agent Orange [PDF]
Environmental Health, 2019 Background Exposure to the herbicide Agent Orange during the Vietnam War was widespread and is associated with numerous adverse health outcomes. A continuing concern of veterans is the possibility that exposure to the dioxin-containing herbicide might ...
Karl T. Kelsey +8 more
doaj +2 more sources
DNA methylation in the adipose tissue and whole blood of Agent Orange-exposed Operation Ranch Hand veterans: a pilot study [PDF]
Environmental Health, 2021 Background Between 1962 and 1971, the US Air Force sprayed Agent Orange across Vietnam, exposing many soldiers to this dioxin-containing herbicide. Several negative health outcomes have been linked to Agent Orange exposure, but data is lacking on the ...
Matthew R. Rytel +5 more
doaj +2 more sources
How Agent Orange impacts prostate cancer risk, pathology, and treatment outcomes [PDF]
Current Urology. Between 2.6 and 3.8 million veterans served in Vietnam while the US military dispersed Agent Orange (AO), although the exact number of exposed individuals is unknown.
Awais Paracha +5 more
doaj +2 more sources