Results 61 to 70 of about 156,721 (286)

A dialogic approach to Toxic Disasters: Agent Orange in A Luoi Valley [PDF]

open access: yesAntropólogos Iberoamericanos en Red, 2019
In the 2000s, a scientific research by a Canadian environmental consulting firm triggered a public health campaign in A Luoi Valley of Central Vietnam.
Tak Uesugi
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Agent Orange and Narratives of Suffering [PDF]

open access: yes, 2012
The Vietnam War (1961-1975) ended almost a half-century ago, and both the United States and Vietnam have put most of it behind them. But the legacy of Agent Orange, the dioxin-containing herbicide that the U.S.
d\u27Aquino, Andrea   +2 more
core   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Congresswoman Barbara Lee Introduces Victims of Agent Orange Relief Act [PDF]

open access: yes, 2013
June 26, 2013 Contact: Carrie Adams (202) 225-2661 Washington, D.C.-- Today, Congresswoman Barbara Lee (D-CA) introduced the Victims of Agent Orange Relief Act of 2013, which would address the ongoing challenges faced by the victims of Agent Orange, four
guerillera
core  

Chemical Diasporas: Legal, Cultural, and Aesthetic Performances of Agent Orange [PDF]

open access: yes, 2020
From 1961 to 1971, the United States military and its allies sprayed a chemical compound, popularly known as Agent Orange, across Vietnam, Cambodia, and Laos during the wars in Southeast Asia. The compound was described by the U.S.
Duong, Natalia
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Recent dioxin contamination from Agent Orange in residents of a southern Vietnam city [PDF]

open access: yes, 2001
Marked elevation of dioxin associated with the herbicide Agent Orange was recently found in 19 of 20 blood samples from persons living in Bien Hoa, a large city in southern Vietnam.
Cao Dai, Le   +7 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

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